Genicular Nerves

2

Review clinical trials related to Genicular Nerves. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study

To compare the effects of the following types of therapy on knee range of motion when given to patients with chronic knee pain: * A standard steroid injection * Peripheral nerve stimulation (PNS) therapy in combination with a standard steroid injection * PNS therapy in combination with a placebo injection Steroid injections are given directly into the knee joints and are considered to be the standard therapy for chronic knee pain. In this study, the injection will be made of the steroid drugs triamcinolone and bupivacaine.

Participants needed: 45
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: M.D. Anderson Cancer CenterUpdated: Mar 3, 2026Locations: 1
Eligibility criteria

Patients diagnosed with chronic knee pain (baseline pain score >=4), seen at Pai... [+2]

Patients with cognitive dysfunction or without capacity to consent [+4]

Status: Recruiting

Cryoneurolysis Prior to Total Knee Arthroplasty (CRYO-TKA Trial)

Approximately 20-30% of patients experience persistent pain after a Total Knee Arthroplasty (TKA). This study investigates whether percutaneous cryoneurolysis of genicular nerves can reduce pain and improve physical function when performed at least 24 hours before surgery. Participants will be randomized to receive either the cryoneurolysis procedure + TKA or TKA only. Results will be tracked for 6 months to see if the intervention improves long-term recovery and quality of life.

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Attikon HospitalUpdated: Feb 20, 2026Locations: 1
Eligibility criteria

Adults ≥18 years undergoing primary TKA for osteoarthritis. [+2]

Cancer-related knee pain. [+2]