Geographic Atrophy from Age-related Macular Degeneration

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Review clinical trials related to Geographic Atrophy from Age-related Macular Degeneration. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Lesion-tailored, Fundus-controlled Perimetry in Geographic Atrophy (GA).

The goal of this observational study is to evaluate changes in retinal sensitivity over time in patients with geographic atrophy due to age related macular degeneration who are receiving pegcetacoplan as part of routine clinical care. The study aims to determine whether lesion tailored fundus-controlled perimetry can reliably measure functional changes near areas of atrophy and whether this testing can be implemented in everyday clinic care over 24 months. Participants will undergo repeated vision testing, standard eye imaging, and visual function questionnaires while continuing their prescribed treatment.

Participants needed: 50
Trial details
Age: 65-90Biological sex: AllType: ObservationalSponsor: University of UtahUpdated: Jun 17, 2026Locations: 1
Eligibility criteria

Age 65-90 years. [+7]

Currently or previously active exudative macular neovascularization in the study... [+4]

Status: Recruiting

Development and Evaluation of Functional Visual Field and Navigation Endpoints in Moderate to Profound Inherited Retinal Disease (DEFINE-IRD)

The Vision Research and Assessment Institute (VRAI) was established with the purpose of serving as a testing facility for efficacy endpoints for patients with Low Vision. The mission of the VRAI is to enable the highest quality, standardized efficacy testing of patients with visual impairment. The VRAI facilitates the development and refinement of existing endpoints specifically for testing patients with Low Vision.

Participants needed: 25
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Ray Therapeutics, Inc.Updated: Mar 31, 2026Locations: 1
Eligibility criteria

Diagnosis of bilateral retinitis pigmentosa (RP) or other retinal dystrophies im... [+2]

Cognitive impairment, memory loss or dementia sufficient in severity to preclude... [+2]

Status: Recruiting

Observational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Patients with Retinal Degeneration

The Vision Research and Assessment Institute (VRAI) was established with the purpose of serving as a testing facility for efficacy endpoints for patients with Low Vision. The mission of the VRAI is to enable the highest quality, standardized efficacy testing of patients with visual impairment. The VRAI facilitates the development and refinement of existing endpoints specifically for testing patients with Low Vision.

Participants needed: 120
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Ray Therapeutics, Inc.Updated: Jan 8, 2025Locations: 1
Eligibility criteria

Diagnosis of bilateral retinitis pigmentosa, choroideremia, Stargardt macular dy... [+2]

Cognitive impairment, memory loss or dementia sufficient in severity to preclude... [+2]