Geographic Atrophy (GA) Secondary to Dry Age-related Macular Degeneration (AMD)

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Review clinical trials related to Geographic Atrophy (GA) Secondary to Dry Age-related Macular Degeneration (AMD). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Phase 1/2 Study to Evaluate the Safety and Efficacy of Intravitreal Administration of BS01 in Patients With Geographic Atrophy Secondary to Dry AMD

This is a Phase 1/2 study, multi-center, dose-escalation interventional study of BS01 in subjects with GA secondary to dry AMD. Part 1 is an open label dose-escalation study; Part 2 is a dose-expansion study with dose(s) selected from Part 1 based on a benefit/risk assessment, and an untreated (sham injection) group to allow for a controlled comparison of efficacy and safety. This is a seamless Phase 1/2 study in up to 10 patients for Phase 1 and 30 patients Phase 2 in patients with GA secondary to dry AMD.

Participants needed: 40
Trial details
Phase: Phase 1, Phase 2Age: 50-85Biological sex: AllType: InterventionalSponsor: Bionic Sight LLCUpdated: Jan 23, 2026Locations: 1
Eligibility criteria

Signed informed consent obtained before screening. [+10]

Previous therapeutic radiation in the region of the SE. [+12]