Gestatiaonl Diabetes Mellitus

6

Review clinical trials related to Gestatiaonl Diabetes Mellitus. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

to Investigate Impact of Diet and Physical Activity Based Nurse Led Interventions on Maternal Outcomes and Neonatal Outcomes in Women With Gestational Diabetes Mellitus (GDM)

Gestational Diabetes Mellitus (GDM) is a growing maternal health concern associated with adverse neonatal outcomes such as macrosomia and shoulder dystocia, often aggravated by poor dietary habits and physical inactivity during pregnancy. This randomized controlled study aims to evaluate the effectiveness of structured nursing interventions focusing on diet and physical activity in improving maternal glycemic control and reducing neonatal complications. A total of 66 pregnant women diagnosed with GDM will be selected through purposive sampling and randomly allocated into intervention and control groups using the lottery method. The intervention group will receive individualized dietary counselling, pregnancy-appropriate physical activity guidance, and regular nursing follow-up, while the control group will continue with routine antenatal care. Maternal outcomes, including fasting blood glucose and HbA1c levels, will be measured at baseline and follow-up visits. Neonatal outcomes such as macrosomia, mode of delivery, and shoulder dystocia will be documented at birth. Data will be collected using structured tools and analysed using SPSS, with independent t-tests and chi-square tests applied. The study anticipates that structured nursing interventions will significantly improve glycaemic control and reduce adverse neonatal outcomes, supporting the integration of evidence-based nursing care into routine GDM management.

Participants needed: 66
Trial details
Age: 18-40Biological sex: FemaleType: InterventionalSponsor: University of Health Sciences LahoreUpdated: Feb 11, 2026Locations: 1
Eligibility criteria

Diagnosed with GDM in the indexed pregnancy [+1]

Pre-existing diabetes mellitus (Type 1 or Type 2) [+4]

Status: Not yet recruiting

Evaluation of Glycemic Impact on Fetal Liver Length and Volume by Ultrasound in Pregnancy

The primary aim of this study is to evaluate whether fetal liver length and volume, as assessed by ultrasound, can serve as reliable markers of the metabolic impact of Gestational Diabetes Mellitus (GDM) on the fetus.

Participants needed: 115
Trial details
Age: 18-52Biological sex: FemaleType: ObservationalSponsor: Assiut UniversityUpdated: Dec 31, 2025Duration: 12 Weeks
Eligibility criteria

gestational age 24wks-36wks by an early pregnancy ultrasound exam including CRL... [+4]

preexisting diabetes [+3]

Status: Recruiting

Shanghai Clinical Cohort of Hyperglycemia in Pregnancy

Establish a high-quality clinical cohort of hyperglycemia in pregnancy. Develop subtype-specific, end-to-end standards for diagnosis, treatment, and follow-up across the preconception, pregnancy, and postpartum phases. These standards will lay a solid foundation for efficient, high-quality clinical research.

Participants needed: 4,000
Trial details
Age: 18+Biological sex: FemaleType: ObservationalSponsor: Shanghai General Hospital, ChinaUpdated: Sep 9, 2025Locations: 1Duration: 10 Years
Eligibility criteria

Pregnant individuals who provide written informed consent [+2]

Current or history of illicit drug use or substance abuse [+2]

Status: Not yet recruiting

Injection Ports vs Single-Use Needles for Insulin in Pregnancy: Effects on Adherence and Satisfaction

This study wants to find out if using an injection port to give insulin during pregnancy helps people take their insulin more regularly and feel better about their care. When someone has diabetes during pregnancy, it's very important to keep their blood sugar levels in a healthy range. This usually means checking blood sugar often and giving insulin through shots. But giving many shots each day can be hard and uncomfortable. An injection port is a small device placed on the skin that lets patients give insulin through the same spot without poking themselves each time. This may make taking insulin easier and less painful. Feeling comfortable with how insulin is given may help people stick to their treatment plan and have better health during pregnancy. Injection ports have already helped other patients, including pregnant people who needed other medications, but they haven't been studied for insulin use during pregnancy. This study will look at how pregnant patients with diabetes feel about using injection ports for insulin.

Participants needed: 44
Trial details
Age: 18-50Biological sex: FemaleType: InterventionalSponsor: University of Texas at AustinUpdated: Sep 10, 2025Locations: 1
Eligibility criteria

Patients with type 2 diabetes mellitus or gestational diabetes who require a mul...

T1DM, primary language non-English or Spanish, use of an insulin pump

Status: Not yet recruiting

Impact of Antepartum Breast Milk Expression on Breastfeeding Rates in Patients With Gestational Diabetes Mellitus

This study proposes a prospective randomized controlled clinical trial involving primiparous women diagnosed with gestational diabetes mellitus (GDM) carrying singleton pregnancies. Participants will be randomized in a 1:1 ratio into either a control group or an intervention group. The control group will receive standard prenatal care followed by routine postpartum breastfeeding guidance. In addition to the standard care provided to the control group, the intervention group will receive one-on-one midwife-led manual breast milk expression training at the breastfeeding clinic. They will begin manual expression twice daily starting at 37 weeks gestation. The primary outcome will compare exclusive breastfeeding rates at 3 months postpartum between groups through postpartum follow-up assessments to evaluate the impact of antenatal milk expression on breastfeeding success in GDM patients.

Participants needed: 212
Trial details
Age: 20-45Biological sex: FemaleType: InterventionalSponsor: Peking University First HospitalUpdated: Aug 19, 2025
Eligibility criteria

Expressed intention for exclusive breastfeeding; Aged 20-45 years; Nulliparous s...

Contraindications to breastfeeding; multifetal pregnancy; placenta previa; prege...

Status: Recruiting

Gongji Pregnancy Endorine Cohort Study

To explore the relationship between genetic factors, lifestyle, and drug interventions and the occurrence, development, adverse pregnancy outcomes, and postpartum maternal-infant outcomes of gestational endocrine diseases.

Participants needed: 3,000
Trial details
Age: 18-50Biological sex: FemaleType: ObservationalSponsor: Shanghai General Hospital, ChinaUpdated: Aug 15, 2025Locations: 1Duration: 10 Years
Eligibility criteria

Women preparing for pregnancy or pregnant women or within 1 year after giving bi... [+2]

Individuals who are unable to communicate normally and those who are unwilling t... [+2]