Health Trials

Glioblastoma of Cerebellum

2

Review clinical trials related to Glioblastoma of Cerebellum. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

This study is a clinical trial to determine the safety of inoculating G207 (an experimental virus therapy) into a recurrent or refractory cerebellar brain tumor. The safety of combining G207 with a single low dose of radiation, designed to enhance virus replication, tumor cell killing, and an anti-tumor immune response, will also be tested. Funding Source- FDA OOPD

Participants needed: 24
Trial details
Phase: Phase 1Age: 3-21Biological sex: AllType: InterventionalSponsor: M.D. Anderson Cancer CenterUpdated: May 15, 2026Locations: 3
Eligibility criteria

Age ≥ 36 months and < 22 years [+12]

Any treatment outside the allowable guidelines outlined in section 5.1. [+10]

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Status: Recruiting

DLL3 CAR-T Therapy Targeting Brain Tumors

The purpose of this study is to assess the feasibility, safety and efficacy of Delta-like ligand 3 (DLL3)-specific CAR-T cell therapy in patients with DLL3 positive brain tumors including glioblastomas and diffused intrinsic pontine or midline gliomas (DIPG or DMG). Another goal of the study is to learn more about the function of the anti-DLL3 CAR-T cells and their persistency in patients.

Participants needed: 30
Trial details
Phase: Phase 1, Phase 2Age: 2-70Biological sex: AllType: InterventionalSponsor: Shenzhen Geno-Immune Medical InstituteUpdated: Sep 18, 2025Locations: 1
Eligibility criteria

abilities to understand and the willingness to provide written informed consent; [+9]

a prior history of gliadel implantation 4 weeks before this study start or curre... [+5]

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