Status: Recruiting
Multicenter Prospective Study on MRI AI Model for Midline Glioma Subtyping and Prognosis:
A vision-language model using preoperative MRI and clinical variables has been developed to simultaneously predict three key molecular markers in midline gliomas: H3K27M, IDH, and 1p/19q. This prospective multicenter study will validate the model's accuracy in preoperative molecular subtyping and its value in prognostic assessment and clinical decision-making across multiple neurosurgical centers.
Participants needed: 500
Trial details
Biological sex: AllType: ObservationalSponsor: Xiangya Hospital of Central South UniversityUpdated: May 27, 2026Locations: 1Duration: 3 Years
Eligibility criteria
Patients with diffuse gliomas were pathologically and molecularly diagnosed. [+2]
The tumor is not located in the intracranial midline. [+1]