Health Trials

Glioma of Brainstem

2

Review clinical trials related to Glioma of Brainstem. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Multicenter Prospective Study on MRI AI Model for Midline Glioma Subtyping and Prognosis:

A vision-language model using preoperative MRI and clinical variables has been developed to simultaneously predict three key molecular markers in midline gliomas: H3K27M, IDH, and 1p/19q. This prospective multicenter study will validate the model's accuracy in preoperative molecular subtyping and its value in prognostic assessment and clinical decision-making across multiple neurosurgical centers.

Participants needed: 500
Trial details
Biological sex: AllType: ObservationalSponsor: Xiangya Hospital of Central South UniversityUpdated: May 27, 2026Locations: 1Duration: 3 Years
Eligibility criteria

Patients with diffuse gliomas were pathologically and molecularly diagnosed. [+2]

The tumor is not located in the intracranial midline. [+1]

Read more
Status: Recruiting

GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas (DIPG) & Spinal Diffuse Midline Glioma(DMG)

The primary purpose of this study is to test whether CAR T cells targeting GD2 (GD2CART) can be successfully made and safely given to children and adults with H3K27M-mutant diffuse midline glioma (DMG). Eligible subjects may have DMG arising in the pons (called difuse intrinisic pontine glioma, DIPG), the spinal cord, or other areas of the brain such as a thalamus

Participants needed: 97
Trial details
Phase: Phase 1Age: 2-60Biological sex: AllType: InterventionalSponsor: Stanford UniversityUpdated: Jan 26, 2026Locations: 1
Eligibility criteria

Disease Status: Diagnosis of H3K27M mutant diffuse midline glioma (DMG) [+11]

For Dose Escalation: Bulky tumor involvement of cerebellar vermis or hemispheres... [+15]

Read more