Haemophilia A (Moderate or Severe)

1

Review clinical trials related to Haemophilia A (Moderate or Severe). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study to Provide Continued Access to Treatment for Patients Completing a Previous Trial With Efanesoctocog Alfa

This is a multinational, prospective, open-label, roll-over study in patients with haemophilia A, ≥6 years of age, who have completed participation in any of the parental studies with efanesoctocog alfa; XTEND-ed study (LTS16294), FREEDOM study (Sobi.BIVV001-001), PK comparison study (Sobi.BIVV001-003) or SHINE study (Sobi.BIVV001-004). The aim of the study is to provide patients with continuous benefit from efanesoctocog alfa treatment and to further continue clinical monitoring for safety and efficacy until efanesoctocog alfa is commercially available in each patient's respective country (or until March 2027, whichever comes first). The study starts with the Baseline Visit, which will be done in connection to the end of treatment at the EoT/EoS visit (or equivalent) in the respective parent study. Subsequent study visits (on site or phone call) will be done approximately every 13 weeks until End of Treatment. An End of Study safety phone call will be done 14 (+7) days after the End of Treatment Visit.

Participants needed: 104
Trial details
Phase: Phase 3Age: 6+Biological sex: MaleType: InterventionalSponsor: Swedish Orphan BiovitrumUpdated: Jun 26, 2026Locations: 21
Eligibility criteria

Capable of giving signed informed consent. Parents or legally designated represe... [+2]

Positive inhibitor result, defined as ≥0.6 Bethesda units (BU)/mL, present at th... [+2]