Hand Surgery

5

Review clinical trials related to Hand Surgery. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Bicarbonate Addition to Lidocaine-Epinephrine in Surgery Under WALANT

Distal upper limb and distal lower limb surgery performed under local anesthesia using the WALANT technique (Wide Awake Local Anesthesia No Tourniquet) has become standard practice in ambulatory orthopedic surgery. Current infiltration mixtures used by orthopedic surgeons include lidocaine-epinephrine with the addition of 8.4% bicarbonate to reduce injection-related pain and improve analgesia duration. However, the clinical benefit of bicarbonate addition remains insufficiently supported by evidence and may increase preparation complexity and risk, including potential solution crystallization. The aim of the ROPIWA-2 trial is to investigate whether omission of bicarbonate from the local infiltration mixture is noninferior to bicarbonate addition with respect to early postoperative quality of recovery on postoperative day 1. We hypothesize that removing bicarbonate does not impair postoperative quality of recovery after ambulatory hand and foot surgery under WALANT. Expected benefits include confirmation of a simpler, ready-to-use anesthetic solution that is easier and safer to use, without reducing patient comfort or recovery. The expected risks are those normally associated with this type of procedure.

Participants needed: 150
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Centre Hospitalier Universitaire de NīmesUpdated: Jan 15, 2026Locations: 1
Eligibility criteria

Adults (≥18 years) eligible for ambulatory surgery under WALANT for Hand surgery... [+3]

Ischemic vascular disorders, including severe Raynaud's disease, Buerger's disea... [+18]

Status: Recruiting

Comparison of Conventional and Retroclavicular Approaches for Ultrasound-guided Infraclavicular Brachial Plexus Block

Forearm and hand surgeries are among the most frequently performed surgical interventions both in trauma patients and electively.In these procedures, alternative anesthesia methods such as general anesthesia, regional intravenous anesthesia, regional peripheral nerve blocks and local anesthesia are available. Peripheral nerve blockade can be used for anesthesia and analgesia.This method allows patients to undergo surgery without general anesthesia and increases patient satisfaction by providing effective analgesia in the postoperative period. The aim of this study was to compare the conventional and retroclavicular approaches to infraclavicular block in patients undergoing forearm and hand surgery.

Participants needed: 60
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Ankara Etlik City HospitalUpdated: Dec 15, 2025Locations: 1
Eligibility criteria

Patients 18-80 years of age [+3]

Patients who cannot perceive and evaluate pain [+2]

Status: Recruiting

Evaluating the Benefit of Hypnoanalgesia Versus Neuroleptanalgesia During Hand Surgery

This is a single-center, prospective, randomized, open-label study of two parallel groups of patients undergoing hand surgery: Group 1: locoregional anesthesia + neuroleptanalgesia Group 2: locoregional anesthesia + hypnoanalgesia Therapeutic benefit is based on VAS assessment of intraoperative anxiety.

Participants needed: 64
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: GCS Ramsay Santé pour l'Enseignement et la RechercheUpdated: Dec 9, 2025Locations: 1
Eligibility criteria

Patients aged between 18 and 80, [+3]

Contraindication to locoregional anaesthesia or to one of the sedatives used in... [+4]

Status: Not yet recruiting

Efficacy of Laser Acupuncture on Carpal Tunnel Syndrome Following Hand Flexor Tendon Repair

The purpose of this study is to determine the efficacy of laser acupuncture in alleviating CTS symptoms following flexor tendon repair in the hand.

Participants needed: 60
Trial details
Age: 20-40Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Jun 11, 2025Locations: 1
Eligibility criteria

Adults aged 20-40 years who have undergone flexor tendon repair surgery. [+4]

Pre-existing neurological disorders. [+11]

Status: Not yet recruiting

Comparison Between Effect of Systemic Fentanyl Infusion and Fentanyl Added as An Adjuvant to Lidocaine in Bier Block For Controlling Pain in Patients Undergoing Hand Surgeries

Injury and deformity of the upper extremity can result in dysfunction to nerves, tendons and bones which can lead to disability and pain. Various techniques of regional anesthesia are frequently used for upper extremity surgery. Specifically, intravenous regional anesthesia, the Bier block, is an effective anesthetic technique. This technique, developed by Dr August Bier in 1908, provides complete anesthesia, a bloodless field, and eliminates the need for general anesthesia. However, it was not until the 1960s that this technique was reintroduced and used in upper extremity surgery due to several disadvantages and reports of major complications. Because of the dose of lidocaine and tourniquet time, there is potential for cardiac and neurological complications such as arrhythmias, seizures, and compartment syndrome the aim of this study To evaluate the effect of Systemic Fentanyl Infusion compared to addition of Fentanyl as An Adjuvant to Lidocaine in Bier Block for Controlling Pain in Patients Undergoing Hand Surgeries

Participants needed: 84
Trial details
Phase: Phase 4Age: 18-40Biological sex: AllType: InterventionalSponsor: Assiut UniversityUpdated: Apr 18, 2025
Eligibility criteria

Patients age from 18 years to 40 years [+3]

• Patients who refuse to participate in study. [+5]