Haplo-identical HCT

2

Review clinical trials related to Haplo-identical HCT. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

CD45RA-depleted DLI for the Prevention of Viral Infections in High-risk Patients After Haploidentical Transplantation

The goal of this clinical trial is to learn whether giving patients a special type of donor immune cells (called CD45RA Depleted DLI) can help prevent viral infections after a stem cell transplant. It will also learn about the safety of this treatment. The main questions it aims to answer are: Does this treatment lower the chance of getting serious viral infections after transplant? What medical problems do patients have when receiving this treatment?

Participants needed: 30
Trial details
Phase: Phase 1Age: 14-50Biological sex: AllType: InterventionalSponsor: Ruijin HospitalUpdated: Jun 29, 2026Locations: 1
Eligibility criteria

Patients undergoing allogeneic hematopoietic stem cell transplantation (any cond... [+14]

Active grade II-IV acute graft-versus-host disease (aGVHD) [+4]

Status: Recruiting

CD45RA-depleted DLI for the Treatment of Refractory/Persistent Viral Infections After Haploidentical Transplantation

The goal of this clinical trial is to learn whether giving patients special donor immune cells (called "CD45RA Depleted DLI") can help treat viral infections that have not improved with standard antiviral drugs. These infections occur after a stem cell transplant. The study will also look at the safety of this treatment.

Participants needed: 30
Trial details
Phase: Phase 1, Phase 2Biological sex: AllType: InterventionalSponsor: Ruijin HospitalUpdated: Jun 23, 2026Locations: 1
Eligibility criteria

Patients who have undergone hematopoietic stem cell transplantation. [+8]

Active grade II-IV acute graft-versus-host disease (aGVHD). [+5]