Head and Neck Cancer (H&Amp;Amp;Amp;N)

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Review clinical trials related to Head and Neck Cancer (H&Amp;Amp;Amp;N). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Endostatin Adenovirus With Checkpoint Inhibitor in Advanced Head and Neck or Esophageal Cancer

This is a Phase I, open-label, dual-cohort clinical trial designed to evaluate the safety, tolerability, and preliminary efficacy of intratumoral injection of recombinant human endostatin adenovirus in combination with a PD-1 inhibitor in patients with recurrent or metastatic head and neck cancer, or in patients with esophageal squamous cell carcinoma (ESCC) with superficial lymph node metastasis.

Participants needed: 40
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Sichuan UniversityUpdated: Sep 4, 2025Locations: 1
Eligibility criteria

Cohort A (Head and Neck Cancer) [+20]

Known allergy or hypersensitivity to study drugs [+16]