Hearing Loss, Bilateral

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Review clinical trials related to Hearing Loss, Bilateral. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Preschool Hearing Screening

Children who are deaf or hard-of-hearing (D/HH) are at risk of speech and language delays, which can be mitigated through early identification and intervention. Identifying hearing loss (HL) during preschool is crucial, but the most effective hearing screening method for preschoolers remains uncertain. The purpose of this study is to learn whether, compared to the gold-standard two-stage Pure-tone audiometry (PTA) + otoacoustic emissions (OAE) screening (TS-PO), single-stage OAE (SS-O) screening alone is not inferior at identifying hearing loss when performed in a community-based preschool setting. This study holds the potential to improve early hearing loss detection and intervention among D/HH children, reducing the likelihood of speech and language delays. A diverse group of 13,764 preschool-age children across community-based preschool centers will be recruited. The intervention involves all subjects undergoing both PTA and OAE screening, with the order determined through randomization. Children who show potential hearing issues based on screening results or teacher concerns will receive further testing to determine the final hearing outcome. Group allocation will be post-hoc, based on their screening results. In addition to the primary objective, the study will compare other hearing screening measures and outcomes between the two methods (TS-PO and SS-O). This approach aims to reflect the real-life effectiveness of hearing screening in a diverse population. Ultimately, the study seeks to provide insights into an optimal hearing screening method that could prevent speech and language delays among D/HH children.

Participants needed: 13,764
Trial details
Age: 2-6Biological sex: AllType: InterventionalSponsor: University of California, San FranciscoUpdated: Feb 2, 2026Locations: 1
Eligibility criteria

Age 2:0 - 6:0 years [+1]

Known permanent HL, by parental or school report [+4]

Status: Recruiting

Sentence Shaping - DHH

The proposed research addresses a long-standing and important challenge of improving literacy skills of children who are deaf and hard of hearing, a historically under researched group. The investigators aim to leverage shape coding - an empirically validated intervention approach for constructing sentences in spoken English - for improving how efficiently children who are deaf and hard of hearing learn to correctly construct sentences in written English. To advance the promising yet underutilized research on shape coding, the investigators complete the next logical step of applying the visual supports provided with shape coding to written language for deaf and hard of hearing children. Shape coding has been effective for teaching sentence structure in spoken English to children with language disabilities and has recently been applied to sentence structure in American Sign Language with deaf and hard of hearing children. Intervention involving shape coding is predicted to result in increased accuracy of word order in sentences in written English because deaf and hard of hearing children often benefit from visual information. The investigators will accomplish this aim using single case multiple probe across participants design studies with 30 fifth through eighth grade children who are deaf and hard of hearing. The knowledge gained will guide language and literacy intervention for children who are deaf and hard of hearing.

Participants needed: 30
Trial details
Age: 9-15Biological sex: AllType: InterventionalSponsor: Vanderbilt UniversityUpdated: Oct 22, 2025Locations: 1
Eligibility criteria

Children in grades five through eight [+5]

diagnosis of dyslexia [+2]

Status: Recruiting

Clinical Utility of Residual Hearing in the Cochlear Implant Ear

The current study is a randomized multi-center clinical trial that investigates the role an intraoperative hearing monitoring system (electrocochleography) has on helping to save residual hearing in patients undergoing cochlear implantation (CI).

Participants needed: 40
Trial details
Age: 18-79Biological sex: AllType: InterventionalSponsor: Ohio State UniversityUpdated: Sep 12, 2025Locations: 5
Eligibility criteria

Provision of signed and dated informed consent form. [+12]

Previous cochlear implantation. [+8]

Status: Recruiting

Speech Understanding and Listening Effort Benefits of Hearing Instruments

The goal of this clinical study is to investigate the benefits of hearing instrument use in adults with hearing loss. The main questions it aims to answer are: Does hearing instrument use improve speech understanding and listening effort amount people with hearing loss? Researchers will compare varying models of hearing instruments to see how speech understanding and listening effort are impacted. Participants will be asked to wearing varying hearing instruments and participate in lab-based activities to evaluate their speech understanding, listening effort, and subjective preference.

Participants needed: 30
Trial details
Age: 18-95Biological sex: AllType: InterventionalSponsor: Sonova AGUpdated: Aug 11, 2025Locations: 1
Eligibility criteria

Adult 18-95 years [+4]

Outside of specified age range [+4]