Heart Failure With Preserved Ejection Fraction (HFpEF; Diagnosis)

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Review clinical trials related to Heart Failure With Preserved Ejection Fraction (HFpEF; Diagnosis). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Prospective Evaluation of AI-ECG for SHD Detection

This study aims to improve the early detection of undiagnosed heart disease, which causes serious health issues, hospital admissions, and high healthcare costs. Researchers are exploring how artificial intelligence (AI) can analyse routine heart tests, called electrocardiograms (ECGs), to detect heart problems. These tests can be done using both traditional ECG machines and portable, wearable devices like smartwatches, making it easier for people to monitor their heart health at home. While AI has shown promise using past data, this study will involve the collection of ECG data and subsequent testing of its accuracy in real-world settings to ensure it works well for both doctors and patients. The goal is to see if AI can identify conditions like heart muscle weakness, valve issues, and high lung pressure from the ECG data of patients. The researchers will also compare AI's detections with other blood tests commonly used to diagnose heart disease. The AI models that will be used are being tested for research and validation purposes only. They will not be used for clinical decision-making or providing information to influence diagnosis, treatment, or patient care during the study. The AI outputs are not shared with clinicians and will have no impact on the care pathway. This research will demonstrate if AI-powered ECG analysis - whether from traditional or portable devices - can provide a low-cost, non-invasive way to detect heart disease early and improve health assessments.

Participants needed: 590
Trial details
Age: 18-90Biological sex: AllType: ObservationalSponsor: Imperial College LondonUpdated: Mar 9, 2026Locations: 5
Eligibility criteria

Patients aged 18-90 years [+2]

Severe arrhythmia or unstable cardiovascular disease [+3]

Status: Recruiting

Heart Failure With Preserved Ejection Fraction in Patients With Сhronic Obstructive Pulmonary Disease: Clinical Course and Prognosis

Study aim is comparison of heart failire with preserved ejection fraction (HFpEF) detection rate in patients with Сhronic Obstructive Pulmonary Disease (COPD) and the clinical course and prognosis in patients with COPD depending on HFpEF presence.

Participants needed: 200
Trial details
Age: 50-70Biological sex: AllType: ObservationalSponsor: National Medical Research Center for Therapy and Preventive MedicineUpdated: Feb 10, 2026Locations: 2
Eligibility criteria

Verified diagnosis of COPD; [+4]

Lack of Russian Federaion citizenship; [+3]