Status: Recruiting
Efficacies of Bismuth-amoxicillin-vonoprazan Triple Therapy, Vonoprazan-amoxicillin Dual Therapy and Proton Pump Inhibitor-based Standard Triple Therapy for Hp Eradication
1. Compare the efficacies and safety of 14-day bismuth-amoxicillin-vonoprazan tiple therapy, 14-day vonoprazan dual therapy and 14-day rabeprazole triple therapy in the first-line treatment of H. pylori infection. 2. To investigate the impacts of antibiotic resistance of H. pylori as well as CYP3A4, CYP2C19 and IL-1B -511 genotypes of host on the eradication efficacies of anti-H. pylori treatments.
Participants needed: 390
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Kaohsiung Medical UniversityUpdated: Jan 15, 2026Locations: 1
Eligibility criteria
Those who have ever received Helicobacter pylori sterilization treatment. [+4]