Health Trials

Hematopoietic Cell Transplantation (HCT)

2

Review clinical trials related to Hematopoietic Cell Transplantation (HCT). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT

The purpose of this study is to test the feasibility and safety of early cessation of tacrolimus following allogeneic hematopoietic cell transplantation (HCT). Post-HCT tacrolimus is given to prevent graft-vs-host-disease (GVHD), but with the use of post-transplant cyclophosphamide (PTCy), the modern approach to GVHD prevention, GVHD rates have reduced markedly.

Participants needed: 50
Trial details
Phase: Phase 1Age: 18-80Biological sex: AllType: InterventionalSponsor: Stanford UniversityUpdated: Apr 17, 2026Locations: 1
Eligibility criteria

Acute myeloid leukemia (AML) in complete remission (CR), CR with incomplete hema... [+12]

Prior allogeneic HCT. [+8]

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Status: Recruiting

Momelotinib During and After HCT in Myelofibrosis

This is a single-center, open-label, phase I study to determine the safety and tolerability of momelotinib in patients with myelofibrosis during and after hematopoietic cell transplantation (HCT).

Participants needed: 28
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Massachusetts General HospitalUpdated: Mar 31, 2026Locations: 1
Eligibility criteria

Participants must have pathologically confirmed primary myelofibrosis (PMF) acco... [+14]

Known intolerance or hypersensitivity to any JAK inhibitor, including ruxolitini... [+26]

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