Hemidiaphragmatic Paralysis

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Review clinical trials related to Hemidiaphragmatic Paralysis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Comparative Evaluation of Diaphragmatic Function Following Interscalene, Anterior Suprascapular, and Costoclavicular Nerve Blocks in Shoulder Surgery

Shoulder surgery causes significant postoperative pain, and ultrasound-guided regional anesthesia is central to its management. The interscalene block (ISB) is the gold standard but frequently causes phrenic nerve paralysis and hemi-diaphragmatic paresis, limiting its use in patients with reduced pulmonary reserve. The suprascapular (SSNB) and costoclavicular (CCB) blocks are proposed diaphragm-sparing alternatives, but data directly comparing all three are limited. This randomised, double-blinded trial will compare the incidence of hemi-diaphragmatic paresis among ultrasound-guided ISB, SSNB, and CCB in elective shoulder surgery. Seventy-five ASA I-II patients aged 18-70 will be allocated 1:1:1 to one block. The primary outcome is the incidence of hemi-diaphragmatic paresis, measured by ultrasound diaphragmatic excursion before induction and after recovery in the PACU. Secondary outcomes include postoperative pain, analgesic consumption, and patient satisfaction. The investigators hypothesise that SSNB and CCB will cause less hemidiaphragmatic paresis than ISB while providing comparable analgesia.

Participants needed: 75
Trial details
Phase: Phase 4Age: 18-80Biological sex: AllType: InterventionalSponsor: Menoufia UniversityUpdated: Jun 26, 2026
Eligibility criteria

Not listed

Status: Recruiting

The Effects of Regional Anaesthesia Techniques on Hemidiaphragm Paralysis, Postoperative Recovery Quality, Opioid Consumption, and Pain Scores

This study aims to evaluate the effects of ultrasound-guided interscalene, erector spinae plane, costoclavicular, and supraclavicular blocks on hemidiaphragmatic paralysis, postoperative recovery quality, opioid consumption, and pain scores.

Participants needed: 88
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Antalya Training and Research HospitalUpdated: May 11, 2026Locations: 1
Eligibility criteria

aged 18-65 years [+3]

ASA score ≥4 [+7]

Status: Not yet recruiting

Shoulder Pericapsular Block Versus Interscalene Block in Arthroscopic Shoulder Surgery

This randomized controlled trial aims to compare the incidence of hemidiaphragmatic paralysis (HDP) following ultrasound-guided interscalene block (ISB) versus shoulder pericapsular nerve group (PENG) block in patients undergoing elective shoulder surgery under general anesthesia. The primary objective is to determine whether the shoulder PENG block reduces the incidence of HDP compared with conventional intrafascial ISB. HDP will be assessed using ultrasound measurement of diaphragmatic excursion 30 minutes after block performance

Participants needed: 70
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Marmara UniversityUpdated: Mar 20, 2026
Eligibility criteria

ASA physical status I-III [+2]

Pre-existing diaphragmatic dysfunction [+7]