Hemiparesis;Poststroke/CVA

6

Review clinical trials related to Hemiparesis;Poststroke/CVA. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Development and Efficacy of a Novel, Cost-Effective Gait Training Device Utilized at Home for Stroke Survivors

This pilot, parallel-group randomized controlled trial will evaluate the feasibility, safety, usability, and preliminary efficacy of the Rise\&Walk InHome (RWH), a novel robotic gait training device designed for home use after stroke. Twenty adults with lower-extremity motor impairment following a first-ever stroke (3 months to 5 years post-event) will be randomized 1:1 to either (1) RWH-assisted home walking plus usual care or (2) usual care alone for 12 weeks. Participants in the intervention group will receive an in-home RWH device, complete a structured device training program, and be instructed to perform 30-minute RWH walking sessions four times per week (48 sessions total). All participants will undergo standardized outcome assessments at baseline, weeks 4, 8, and 12, including the 6-Minute Walk Test (primary outcome), 10-Meter Walk Test, daily step count via wearable activity tracker, and health-related quality of life (SF-36). Additional feasibility and usability outcomes include device use and adherence, patient satisfaction and motivation, ease of use, perceived exertion, and adverse events. Findings will inform the feasibility of in-home deployment of the RWH device and provide preliminary effect-size estimates to guide the design of a larger efficacy trial.

Participants needed: 20
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Healing InnovationsUpdated: Mar 9, 2026Locations: 1
Eligibility criteria

Age ≥ 18 years. [+8]

Unstable cardiovascular, respiratory, or other medical conditions that contraind... [+6]

Status: Recruiting

A Novel Wrist Wearable Sensor System to Promote Hemiparetic Upper Extremity Use in Subacute Stroke Survivors

The proposed study is a two-arm randomized clinical trial designed to assess the effects of the StrokeWear system on clinical outcomes over a period of 6-months in subacute stroke survivors. The Intervention group will use StrokeWear system in combination to a motor and behavioral home intervention whereas the Control group will follow usual care which consists of a home-exercise plan (HEP).

Participants needed: 88
Trial details
Age: 18-85Biological sex: AllType: InterventionalSponsor: Spaulding Rehabilitation HospitalUpdated: Nov 28, 2025Locations: 1
Eligibility criteria

Male or female, 18-85 years of age at the time of enrollment [+5]

Severe spasticity (defined as a Modified Ashworth scale score of 3 or more) that... [+8]

Status: Recruiting

Novel Wrist Sensor System to Promote Hemiparetic Arm Use in Home Daily Life of Chronic Stroke Survivors

The proposed study is a two-arm randomized clinical trial designed to assess the effects of the StrokeWear system on clinical outcomes over a period of 6-months in chronic stroke survivors. The Intervention group will use StrokeWear system in combination to a motor and behavioral home intervention whereas the Control group will follow usual care which consists of a home-exercise plan (HEP).

Participants needed: 32
Trial details
Phase: Phase 2Age: 18-85Biological sex: AllType: InterventionalSponsor: Spaulding Rehabilitation HospitalUpdated: Nov 28, 2025Locations: 1
Eligibility criteria

Male or female, 18-85 years of age at the time of enrollment; [+4]

Severe spasticity (defined as a Modified Ashworth scale score of 3 or more) that... [+10]

Status: Recruiting

Effects of Functional Electrical Stimulation Assisted Cycling in Patients With Hemiparesis After Stroke

To determine whether active cycling assisted by functional electrical stimulation (FES) Is more effective than active cycling on cardiovascular fitness in post stroke hemiparesis

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: UGECAM Rhône-AlpesUpdated: Sep 19, 2025Locations: 1
Eligibility criteria

Adults with Hemiparesis after an unilateral first ever stroke [+3]

Any history of neurological disorders or cardiovascular instability [+3]

Status: Recruiting

Effects of Atalante Exoskeleton on Gait Recovery in Non- or Poorly Ambulatory Patients With Hemiparesis in the Acute/Subacute Phase (Month 1 to 4)

The present clinical investigation - EarlyExo, is an interventional, international, multicentric, prospective, single-blinded randomized controlled trial. This clinical investigation is designed to test the hypothesis that early and intense introduction of walking sessions assisted by the Atalante exoskeleton, in a sample of hemiparetic patients with still non or poor ambulatory capacities (FAC 0 or 1) between one- and four-months post stroke, would result in a better recovery of functional walking compared to a control group only receiving conventional therapy. Improved recovery will be measured through the proportion of patients reaching a FAC score of 4 or higher at the end of the intervention period. The tested hypothesis is that this proportion will be higher in the Exo group. The duration of the intervention period in both groups is 6 weeks. * For the Exo group: 3 sessions per week (i.e., 18 one-hour sessions) with the Atalante device and 2 sessions per week (i.e., 12 one-hour sessions) of conventional therapy. * For the Control group: 5 sessions per week of conventional therapy (i.e., 30 one-hour sessions). The study will include 66 patients (33 in each arm) and takes place in two French centers, two German centers and one Spanish center.

Participants needed: 66
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: WandercraftUpdated: Feb 4, 2025Locations: 5
Eligibility criteria

>18 years old [+5]

Muscle overactivity in hip adductors, hamstrings, quadriceps and plantar flexors... [+10]

Status: Recruiting

Associative Peripheral Stimulation for Reduction of Motor Impairment During Acute Period of Stroke Recovery

Associative Peripheral Stimulation (APS) is a non-invasive therapy intended for stroke rehabilitation involving transcutaneous electrical muscle stimulation paired with voluntary movement. This pilot study investigates whether APS applied during the acute phase of stroke recovery may reduce impairment and improve function in the affected upper extremity.

Participants needed: 20
Trial details
Age: 18-79Biological sex: AllType: InterventionalSponsor: Ahmed A. RahimUpdated: Aug 30, 2024Locations: 3
Eligibility criteria

Confirmed ischemic or hemorrhagic stroke no earlier than 7 days prior to enrollm... [+4]

Contraindications, intolerance, or high sensitivity to the experimental protocol... [+4]