Status: Recruiting
The Treatment of Bioartificial Liver With hiHep Cells After Extensive Hepatectomy
It is a prospective, non-randomized, single-arm cohort study. A total of 10 patients will be included in this study. Based on standardized treatment, the treatment of bioartificial liver device will be applied 48-72 hours after extensive hepatectomy. The bioartificial liver device consists of clinical-grade human-induced hepatocytes (hiHep) generated from human fibroblasts via transdifferentiation. In order to evaluate the security and effectiveness of the device, liver function, liver volume, the incidence of liver failure and other results will be analyzed.
Participants needed: 10
Trial details
Phase: Early Phase 1Age: 30-80Biological sex: AllType: InterventionalSponsor: Sir Run Run Shaw HospitalUpdated: Jun 26, 2025Locations: 1
Eligibility criteria
Diagnosed as liver cancer, hepatolithiasis, benign liver tumor, with clear indic... [+3]
In the late stage of the disease, patients with frequent symptoms such as cerebr... [+15]