HER2-Positive Advanced Solid Tumor

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Review clinical trials related to HER2-Positive Advanced Solid Tumor. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

This is a dose-escalation and dose-expansion Phase 1/2a trial to evaluate the safety and tolerability of DB-1303/BNT323 in subjects with advanced solid tumors that express HER2.

Participants needed: 796
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: DualityBio Inc.Updated: Jan 28, 2026Locations: 102
Eligibility criteria

Has a pathologically documented HER2-positive or HER2-expressing (except for coh... [+7]

History of symptomatic CHF (New York Heart Association [NYHA] classes II-IV) or... [+9]