Health Trials

High Grade Non-Hodgkin's Lymphoma, Adult

2

Review clinical trials related to High Grade Non-Hodgkin's Lymphoma, Adult. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

This is a Phase II study of allogeneic hematopoietic stem cell transplant (HCT) using a myeloablative preparative regimen (of either total body irradiation (TBI); or, fludarabine/busulfan for patients unable to receive further radiation). followed by a post-transplant graft-versus-host disease (GVHD) prophylaxis regimen of post-transplant cyclophosphamide (PTCy), tacrolimus (Tac), and mycophenolate mofetil (MMF).

Participants needed: 300
Trial details
Phase: Phase 2Age: Up to 60Biological sex: AllType: InterventionalSponsor: Masonic Cancer Center, University of MinnesotaUpdated: Jun 25, 2026Locations: 1
Eligibility criteria

Age: ≤ 60 years of age [+41]

Chemotherapy refractory large cell and high grade NHL (i.e., progressive disease... [+8]

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Status: Recruiting

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

This is a phase II, open-label, prospective study of T cell receptor alpha/beta depletion (TCR α/β TCD) peripheral blood stem cell (PBSC) transplantation for children and adults with hematological malignancies. This is a safety/feasibility study of the investigational procedure/product.

Participants needed: 70
Trial details
Phase: Phase 2Age: Up to 60Biological sex: AllType: InterventionalSponsor: Masonic Cancer Center, University of MinnesotaUpdated: Apr 6, 2026Locations: 1
Eligibility criteria

Histological confirmation of hematological malignancies [+7]

Pregnant or breastfeeding. [+5]

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