Health Trials

High Grade Serous Adenocarcinoma of Ovary

2

Review clinical trials related to High Grade Serous Adenocarcinoma of Ovary. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers.

Participants needed: 200
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Volastra Therapeutics, Inc.Updated: Nov 4, 2025Locations: 14
Eligibility criteria

All Parts: Age ≥ 18 years, ECOG Performance Status ≤ 1, at least 1 site of measu... [+2]

MSI-H, dMMR, POLE gene hotspot mutated, or known hypermutator phenotype [+6]

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Status: Not yet recruiting

First-line Maintenance Treatment With Fluzoparib Plus Bevacizumab in Advanced BRCA Wild Type Ovarian Cancer

This is an open-label, multi-center Phase II study of fluzoparib combined with bevacizumab for maintenance therapy after first-line platinum-containing chemotherapy in patients with BRCA wild-type advanced ovarian cancer. The primary objective is to evaluate median progression free survival of fluzoparib plus bevacizumab.

Participants needed: 44
Trial details
Phase: Phase 2Age: 18+Biological sex: FemaleType: InterventionalSponsor: Sun Yat-sen UniversityUpdated: Oct 2, 2023Locations: 1
Eligibility criteria

Signed informed consent and ability to comply with treatment and follow-up. [+18]

Previous (within 5 years) or concurrent with other uncured malignant tumors, exc... [+17]

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