Hip Pain Chronic

7

Review clinical trials related to Hip Pain Chronic. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

PENG Block Variants With Dexamethasone and Dexmedetomidine in Older Adults

This study will compare three different versions of the Pericapsular Nerve Group (PENG) block in adults aged 65 years and older who are undergoing surgery for hip conditions. The PENG block is a regional anesthesia technique that can reduce pain after surgery and decrease the need for strong opioid pain medications. All patients in the study will receive the PENG block with 20 mL of 0.2% ropivacaine, but they will be divided into three groups based on the additional medications used: Group 1: PENG block with ropivacaine plus 4 mg of dexamethasone given intravenously. Group 2: PENG block with ropivacaine plus 25 micrograms of dexmedetomidine given near the nerves and 4 mg of dexamethasone given intravenously. Group 3: PENG block with ropivacaine plus 25 micrograms of dexmedetomidine and 4 mg of dexamethasone given near the nerves. Both dexmedetomidine and dexamethasone are medications that may improve the strength and duration of nerve blocks. The main goal of this study is to determine which combination provides the best pain control after hip surgery, reduces the need for opioid medications, and improves patient comfort and recovery. We also aim to evaluate the safety and side-effects of each technique. We hypothesize that adding both dexmedetomidine and dexamethasone near the nerves will provide the longest and most effective pain relief when compared to intravenous administration alone. This trial may help identify the most effective PENG block formula for older adults undergoing hip surgery and could improve pain management, decrease complications related to opioids, and support faster recovery.

Participants needed: 120
Trial details
Age: 65-100Biological sex: AllType: InterventionalSponsor: Poznan University of Medical SciencesUpdated: May 22, 2026Locations: 1
Eligibility criteria

Age 65 years or older [+5]

Patient refusal or inability to provide informed consent [+11]

Status: Not yet recruiting

HIPS Feasibility Randomized Controlled Trial

The goal of this clinical trial is to conduct a randomized controlled trial (RCT) to test the feasibility of two dose- and time-matched pain management programs, delivered via live video, for adults with chronic (lasting at least 3 months) and non-arthritic hip-related pain (HRP). Following pre-determined benchmarks, findings from this trial will be used to assess the feasibility, credibility, and acceptability of both programs (HIPS-1, HIPS-2). In preparation for a future clinical trial powered to test efficacy, we will optimize the protocol for patient recruitment, study protocol, and fidelity materials.

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Massachusetts General HospitalUpdated: May 15, 2026Locations: 1
Eligibility criteria

Presenting with chronic (lasting ≥3 months) hip joint-related pain [+9]

Previous surgery on the symptomatic (painful) hip [+1]

Status: Recruiting

PENG vs L-ESPB With S-ESPB for Analgesia in Total Hip Arthroplasty

The goal of this clinical trial is to evaluate whether different types of regional anesthesia can improve pain control and functional recovery after total hip arthroplasty in adult patients undergoing elective hip replacement surgery. The main questions it aims to answer are: Does the PENG block reduce opioid use in the first 48 hours after surgery more effectively than the combined L-ESPB + S-ESPB technique? Which method provides better pain relief, preserves muscle strength, and supports earlier mobilization? Researchers will compare the Pericapsular Nerve Group (PENG) block with the combination of Lumbar and Sacral Erector Spinae Plane Blocks (L-ESPB + S-ESPB) to see which provides better pain control, fewer side effects, and faster recovery. Participants will: Be randomly assigned to receive one of the two types of ultrasound-guided regional anesthesia Undergo standard hip replacement surgery under spinal anesthesia Be monitored for pain scores, opioid use, time to first walking, muscle strength, satisfaction, and side effects over the first 48 hours after surgery.

Participants needed: 90
Trial details
Phase: Phase 4Age: 65-100Biological sex: AllType: InterventionalSponsor: Poznan University of Medical SciencesUpdated: May 7, 2026Locations: 1
Eligibility criteria

Age ≥ 65 years [+3]

Allergy to study drugs (ropivacaine, dexamethasone) [+5]

Status: Not yet recruiting

Psychosocial Interventions for Young Adults With Hip Pain

Psychosocial conditions are common in young adults with hip pain including depression, anxiety, pain catastrophizing, and narcotic use. The incidence of these conditions is not well defined. Interventions to optimize psychosocial conditions with non-surgical or surgical treatments has not been investigated. The goal of this project is to determine the incidence of psychosocial conditions in the young adult population with hip pain and determine if cognitive based therapy can improve clinical outcomes in these individuals.

Participants needed: 150
Trial details
Age: 15-39Biological sex: AllType: InterventionalSponsor: Michael C WilleyUpdated: Apr 15, 2026Locations: 1
Eligibility criteria

We will enroll young adults (15-39) presenting to one of several physical therap... [+1]

Exclusion criteria will include age <15 or >40 years [+2]

Status: Recruiting

Education and Exercise for Patients With Longstanding Hip and Groin Pain

Longstanding hip and groin pain (LHGP) is a common and debilitating problem in young to middle aged individuals. These patients often get referred to orthopedic departments. Consensus statements on the management of these patients commonly recommend a physical therapist-led intervention as the first line intervention. However, the optimal content and delivery of this intervention is currently unknown. In this study we will compare the effectiveness of usual care (unstructured physical therapist-led intervention) to a semi-structured, progressive individualized physical therapist-led intervention on hip-related quality of life in people with longstanding hip and groin pain referred to an orthopedic department.

Participants needed: 122
Trial details
Age: 18-55Biological sex: AllType: InterventionalSponsor: Lund UniversityUpdated: Apr 2, 2026Locations: 1
Eligibility criteria

Men and women aged 18-55 years [+3]

Groin pain originating from any diagnosis with other treatment pathways, i.e., i... [+2]

Status: Recruiting

MDR - PMCF Study for Taperloc Complete Stems

The objective of this consecutive series PMCF study is to collect data confirming safety, performance, and clinical benefits of the Taperloc Complete stems when used for primary or revision total hip arthroplasty (implants) at 1,3,5,7 and 10-year follow-up\*. Since Taperloc Complete was introduced to the EU in 2010, all available retrospective data will be collected from each patient and a prospective aspect to the study will be necessary to reach the 10-year time point.

Participants needed: 820
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Zimmer BiometUpdated: Mar 11, 2025Locations: 3
Eligibility criteria

Patient must be 18 years of age or older and skeletally mature [+5]

Off-label use [+14]

Status: Recruiting

Continuous Radiofrequency in Hip Osteoarthritis Pain: A Randomized Clinical Trial.

This will be a prospective, single-center, double-blinded, randomized study designed to compare the efficacy of the intraarticular injection of a corticosteroid and the Conventional Radiofrequency (CRF) of the anterior sensory branches to the hip in controlling pain and improving function related to hip osteoarthritis.

Participants needed: 70
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of BrasiliaUpdated: Jan 24, 2024Locations: 1
Eligibility criteria

Individuals ≥ 18 years of age, with symptomatic unilateral hip osteoarthritis, g...

Individuals with radiculopathy and ipsilateral irradiation, osteonecrosis of the...