Homeostatic Iron Regulator Gene-related Hereditary Hemochromatosis

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Review clinical trials related to Homeostatic Iron Regulator Gene-related Hereditary Hemochromatosis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis

This is a phase 2, multicenter, randomized, placebo-controlled, double-blind, parallel-group, proof-of-concept study to assess vamifeport in adult participants with homeostatic iron regulator gene-related hereditary hemochromatosis (HFE-HH). The primary objective of the study is to assess the effect of vamifeport treatment on magnetic resonance imaging (MRI)-based liver iron concentration (LIC) in adult participants with HFE-HH.

Participants needed: 84
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: CSL BehringUpdated: Jun 26, 2026Locations: 98
Eligibility criteria

Adult (≥ 18 years) and has provided written informed consent. [+5]

Clinically relevant laboratory abnormalities, 12-lead electrocardiogram (ECG) fi...