Status: Recruiting
The GENPET Study - An Imaging Study of FCH-PET-CT in Men With Prostate Cancer and a DNA Repair Gene Mutation.
The aim of the study is to determine if PET-CT imaging (using contrast recommended in clinical guidelines) is superior to combined bone scan and MRI/CT of the abdomen \& pelvis in detecting the increased incidence of metastasis (nodal/distant outside the pelvis) in men with prostatic carcinoma with mutations in any of the following germline DNA repair genes BRCA1, BRCA2, MSH2, MSH6, MLH1, PMS2, CHEK2, PALB2, ATM.
Participants needed: 50
Trial details
Age: 18+Biological sex: MaleType: ObservationalSponsor: Institute of Cancer Research, United KingdomUpdated: Dec 16, 2025Locations: 1
Eligibility criteria
Confirmed pathogenic germline mutation in any of the following genes BRCA1, BRCA... [+4]
Diagnosis of other malignancy (excluding basal cell cancer/squamous cell cancer... [+6]