Status: Recruiting
E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers
This is a phase II clinical trial to assess the clinical activity of immunotherapy with E7 TCR-T cells for metastatic HPV-associated cancers. HPV-associated cancers in include cervical, throat, penile, vulvar, vaginal, anal, and other cancers. Participants will receive a conditioning regimen, E7 TCR-T cells, and aldesleukin. Clinical response to treatment will be determined.
Participants needed: 20
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Christian HinrichsUpdated: Jun 12, 2026Locations: 3
Eligibility criteria
Histologically or cytologically confirmed metastatic or refractory/recurrent HPV... [+22]
Uncontrolled intercurrent illness such as active infection, symptomatic congesti... [+17]