Health Trials

HSIL, High Grade Squamous Intraepithelial Lesion

2

Review clinical trials related to HSIL, High Grade Squamous Intraepithelial Lesion. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

CASCADE 2002: PROTECT Study, "PRObiotics to TrEat Anal preCancer Trial

This study is focused on treatment of anal high-grade squamous intraepithelial lesions (HSIL) in persons with HIV (PWH), with the ultimate goal of applying the approach toward prevention of anal cancer in this population

Participants needed: 90
Trial details
Phase: Phase 2Age: 21+Biological sex: AllType: InterventionalSponsor: University of California, San FranciscoUpdated: May 1, 2026Locations: 2
Eligibility criteria

Signed informed consent [+13]

History of any anogenital cancer. [+18]

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Status: Not yet recruiting

Multicenter Prospective Non-randomized Controlled Study of Ella Photodynamic Therapy for Cervical HSIL/CIN2

This study evaluates the efficacy and safety of ALA-PDT versus LEEP in treating cervical HSIL/CIN2, aiming to demonstrate non-inferiority in clinical efficacy.

Participants needed: 560
Trial details
Age: 25-65Biological sex: FemaleType: InterventionalSponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityUpdated: Dec 29, 2025Locations: 5
Eligibility criteria

Female, 25-60 years, understands study procedures and consents to participate; [+2]

Cytology showing ASC-H, HSIL, AGC, or AIS; or evidence of malignant cells on cyt... [+9]

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