Hyperpigmentation

6

Review clinical trials related to Hyperpigmentation. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Evaluation of Efficacy and Tolerabilty of MelaB3 Serum in Combination of 35% Glycolic Acid Peeling Compared to 35% Glycolic Acid Peeling Alone in Various Hyperpigmentation Conditions

Randomized clinical trial to assess the effectiveness and tolerability of Mela B3 serum in combination with 35% glycolic acid peel vs. 35% glycolic acid peel for the treatment of various hyperpigmentation conditions (melasma, post-inflammatory hyperpigmentation and solar lentigo) and signs of aging in a population of participants from the Autonomous City of Buenos Aires, Argentina.

Participants needed: 80
Trial details
Age: 30-70Biological sex: AllType: InterventionalSponsor: Cosmetique Active InternationalUpdated: Feb 24, 2026
Eligibility criteria

Women and men [+9]

Pregnant, breastfeeding or with pregnancy plans. [+18]

Status: Not yet recruiting

Clinical Study to Assess Safety, Effectiveness and In-Use Tolerability of Saffron Extract Capsules for Improving Skin Health and Reducing Signs of Aging on Healthy Adult Male and Female Subjects.

This is a randomized, double-blind, comparative, two-arm, prospective, interventional, multi-centre clinical study to evaluate the safety, efficacy, and in-use tolerability of test products, standardized saffron extract capsules, on skin rejuvenation and age-defying benefits in healthy adult male and female subjects.

Participants needed: 50
Trial details
Age: 30-55Biological sex: AllType: InterventionalSponsor: NovoBliss Research Pvt LtdUpdated: Jan 7, 2026
Eligibility criteria

Age: 30 to 55 years (both inclusive) at the time of consent. [+8]

Subjects who are on steroids for last six months and using immunosuppressive, an... [+11]

Status: Recruiting

The Effectiveness of a Novel Lip Product Containing Caulerpa Lentillifera Extract for Reducing Lip Hyperpigmentation

The goal of this clinical trial is to evaluate the efficacy of the novel lip product containing Caulerpa lentillifera extract on the appearance and perception of dark lips in Thai adults aged 18 to 60 who report concerns about darkened lips. The main question it aims to answer is: Can the novel lip product containing C. lentillifera extract will significantly improve the appearance and perception of dark lips in Thai adults by reducing hyperpigmentation compared to baseline measurements? Participants will apply the lip product twice a day, in the morning after breakfast and before bedtime, and refrain from using other lip products throughout the clinical trial period (7 days). Researchers will compare the result to baseline measurements

Participants needed: 30
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Chulalongkorn UniversityUpdated: Jul 16, 2025Locations: 1
Eligibility criteria

Understand the study protocol and provide informed consent after being informed... [+1]

Have a known allergy or sensitivity to cosmetic products or Caulerpa lentillifer... [+2]

Status: Recruiting

Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color

The investigators aim to investigate the efficacy and tolerability of a hybrid non-ablative/ablative laser for acne scarring in skin of color.

Participants needed: 46
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Albert Einstein College of MedicineUpdated: May 22, 2025Locations: 1
Eligibility criteria

Healthy males and females, ≥ 18 years of age at time of informed consent, seekin... [+6]

Subjects does not have the capacity to consent to the study [+11]

Status: Recruiting

Efficacy and Tolerability of Tested Formula After 3 Months of Treatment of Facial Hyperpigmentation of 3 Origins

The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to moderate melasma, or mild to moderate acne induced post-inflammatory hyperpigmentation, or solar lentigo.

Participants needed: 72
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Cosmetique Active InternationalUpdated: Aug 6, 2024Locations: 1
Eligibility criteria

all phototypes [+3]

female patient who gave birth less than 3 months prior to Day 0, who is pregnant... [+7]

Status: Recruiting

Efficacy and Tolerability of the Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 Origins

The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to moderate melasma, or mild to moderate acne induced post-inflammatory hyperpigmentation, or solar lentigo.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Cosmetique Active InternationalUpdated: Jul 12, 2024Locations: 1
Eligibility criteria

all phototypes [+3]

female patient who gave birth less than 3 months prior to Day 0, who is pregnant... [+7]