Health Trials

Hypochondroplasia

5

Review clinical trials related to Hypochondroplasia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of Vosoritide Versus Placebo in Children With Hypochondroplasia Aged 0 to < 36 Months

The purpose of this study is to evaluate the safety and efficacy of daily administration of vosoritide in participants with HCH aged 0 to \< 36 months over a 52-week period.

Participants needed: 60
Trial details
Phase: Phase 2Age: 0-36Biological sex: AllType: InterventionalSponsor: BioMarin PharmaceuticalUpdated: Mar 31, 2026Locations: 26
Eligibility criteria

Participants must be 0 to < 36 months of age at randomization. [+3]

Short stature condition other than HCH (eg, ACH, trisomy 21, pseudoachondroplasi... [+10]

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Status: Recruiting

Prospective Longitudinal Monocentric Study to Measure Limb Movement in Patients With FGFR3-related Skeletal Dysplasia

The study aims to identify which Syde®-derived digital outcomes are reliable in FGFR3-related Skeletal Dysplasia. This requires to set-up a natural history study to measure limb movements in patients with ACH or HCH.

Participants needed: 40
Trial details
Age: 3-65Biological sex: AllType: ObservationalSponsor: SYSNAVUpdated: Feb 20, 2026Locations: 1
Eligibility criteria

Aged 3 years old or older at the time of consent. [+6]

Subjects who have short stature condition other than ACH/HCH. [+8]

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Status: Recruiting

Prospective Clinical Assessment Study in Children With Hypochondroplasia

This is a long-term, multicenter, non-interventional study of children ages 2.5 to \<17 years with hypochondroplasia (HCH).

Participants needed: 150
Trial details
Age: 30-16Biological sex: AllType: ObservationalSponsor: QED Therapeutics, a BridgeBio companyUpdated: Oct 10, 2025Locations: 25
Eligibility criteria

Not listed

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Status: Recruiting

A Multicenter Multinational Observational Study of Children With Hypochondroplasia

This study will assess growth over time and the clinical course of HCH in children by collecting growth measurements and other variables of interest.

Participants needed: 400
Trial details
Age: Up to 15Biological sex: AllType: ObservationalSponsor: BioMarin PharmaceuticalUpdated: Apr 3, 2025Locations: 43
Eligibility criteria

Participants must be ≤ 15 years old at the time of signing the informed consent [+1]

Have a diagnosis of another genetic short stature condition other than Hypochond... [+1]

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Status: Recruiting

Registry for Patients With Achondroplasia / Hypochondroplasia (OMPR-Ach/Hy)

This registry is a observational, single-center study designed to collect clinical data on patients with achondroplasia and hypochondroplasia.

Participants needed: 200
Trial details
Biological sex: AllType: ObservationalSponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore PoliclinicoUpdated: Apr 28, 2022Locations: 1Duration: 10 Years
Eligibility criteria

Confirmed diagnosis of achondroplasia/hypochondroplasia [+1]

Absence of diagnosis of achondroplasia/hypochondroplasia [+1]

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