Health Trials

Hypoglycemia Unawareness

2

Review clinical trials related to Hypoglycemia Unawareness. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Regulation of Brain Glucose Metabolism in Type 1 Diabetes

This is a prospective randomized placebo-controlled double-blind crossover pilot study determining the effect of dichloroacetate on brain function under clamped hypoglycemia in T1DM.

Participants needed: 16
Trial details
Phase: Early Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: Yale UniversityUpdated: Jun 9, 2026Locations: 1
Eligibility criteria

a history of severe hypoglycemia and/or hypoglycemia unawareness or [+2]

Age < 18 years or >55 years. [+4]

Read more
Status: Recruiting

Restoration of Hypoglycemia Awareness With Metoclopramide

Metoclopramide is a drug approved by the FDA for gastroesophageal reflux and to relieve symptoms in adults with acute and recurrent diabetic gastroparesis. The objective of this study is to determine whether metoclopramide can improve hypoglycemia awareness and decrease the incidence of hypoglycemia in type 1 diabetes patients with hypoglycemia unawareness.

Participants needed: 36
Trial details
Phase: Phase 2Age: 20-60Biological sex: AllType: InterventionalSponsor: Simon FisherUpdated: Mar 20, 2026Locations: 2
Eligibility criteria

Subjects with Type 1 Diabetes Mellitus [+3]

History of myocardial infarction, cardiac arrhythmia, congestive heart failure a... [+11]

Read more