Hysterotomy; Affecting Fetus

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Review clinical trials related to Hysterotomy; Affecting Fetus. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Effect of Preventive Analgesia by Injection of a Local Anesthetic Before Vaginal Incision for Hysterectomy by vNOTES Approach

The research procedure is the injection of 20 mL of Ropivacaine solution (vs. saline) to create a paracervical block at the beginning of surgery, while the patient is already under general anesthesia. This injection will take place 3 minutes before the vaginal incision, via 4 injection points. Injections are made 3 mm deep into the vaginal cul de sac. Randomization takes place before surgery by vNOTES: * Experienced group: Local anesthesia with injection of Ropivacaine (20mL of ropivacaine 7.5 mg/mL, i.e. 150mg) and general anesthesia * Control group: Injection of 20mL of placebo (saline) and general anesthesia In both groups, systematic intraoperative and postoperative analgesia will be identical.

Participants needed: 108
Trial details
Phase: Phase 3Age: 18-70Biological sex: FemaleType: InterventionalSponsor: University Hospital, RouenUpdated: Jun 8, 2026Locations: 2
Eligibility criteria

Adult patients aged 18 to 70 inclusive [+3]

Suspicion of malignant pathology [+11]