Health Trials

Idiopathic Inflammatory Myopathies(IIM)

2

Review clinical trials related to Idiopathic Inflammatory Myopathies(IIM). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of LUCAR-G79D in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus (r/r SLE) and Idiopathic Inflammatory Myopathies (r/r IIM)

This is a prospective, single-arm, open-label and dose-escalation investigator initialed study to evaluate LUCAR-G79D in adult subjects with r/r SLE and r/r IIM.

Participants needed: 38
Trial details
Phase: Phase 1Age: 18-70Biological sex: AllType: InterventionalSponsor: Nanjing Legend Biotech Co.Updated: Feb 2, 2026Locations: 5
Eligibility criteria

Subjects voluntary agreement to provide written informed consent. [+9]

Active infections such as hepatitis and tuberculosis. [+4]

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Status: Recruiting

An Exploratory Study of CD19/CD22/BCMA CAR-T Cells (BZE2204) in Subjects With Relapsed or Refractory Autoimmune Diseases

This is a single arm, open-label, dose escalation and expansion study to evaluate the safety, tolerability and preliminary efficacy of autologous chimeric antigen receptor T (CAR-T) cells targeting CD19/CD22/BCMA(BZE2204) in patients with relapsed or refractory active autoimmune diseases, including idiopathic inflammatory myopathies(IIM), immune thrombocytopenia(ITP), systemic lupus erythematosus(SLE).

Participants needed: 20
Trial details
Phase: Early Phase 1Age: 18-70Biological sex: AllType: InterventionalSponsor: Shanghai Cell Therapy Group Co.,LtdUpdated: Sep 16, 2025Locations: 1
Eligibility criteria

Males or females, aged 18-70 years old [+26]

A history of severe hypersensitivity or allergic reactions, or contraindications... [+18]

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