Idiopathic Subglottic Tracheal Stenosis

2

Review clinical trials related to Idiopathic Subglottic Tracheal Stenosis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Voice Quality Analysis of Patients With Laryngotracheal Stenosis

The investigators previously demonstrated that voice changes are common in patients with Laryngotracheal Stenosis (LTS), and patients typically report an improvement in voice outcomes following endoscopic dilation. Recently, NIH based programs such as a Bridge to Artificial Intelligence (Bridge2AI) have highlighted the use of artificial intelligence to identify acoustic biomarkers of disease. Therefore, the investigators hypothesize that progression of LTS scar can be quantified using acoustic measurements and machine learning. The goal of this clinical trial is to remotely monitor patient voice quality in an effort to determine if regularly performed voice recordings can be used as a diagnostic tool in order to predict the need for dilation procedures. The investigators feel that successful use of remote voice recording technology with algorithmic analysis will improve patient quality of life.

Participants needed: 100
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Johns Hopkins UniversityUpdated: Jul 13, 2026Locations: 1
Eligibility criteria

Current diagnosis of laryngotracheal stenosis [+4]

Inability to use the app associated with the study. [+2]

Status: Not yet recruiting

Voice Quality Analysis of Patients With Laryngotracheal Stenosis

The investigators previously demonstrated that voice changes are common in patients with Laryngotracheal Stenosis (LTS), and patients typically report an improvement in voice outcomes following endoscopic dilation. Recently, NIH based programs such as a Bridge to Artificial Intelligence (Bridge2AI) have highlighted the use of artificial intelligence to identify acoustic biomarkers of disease. Therefore, the investigators hypothesize that progression of LTS scar can be quantified using acoustic measurements and machine learning. The goal of this clinical trial is to remotely monitor patient voice quality in an effort to determine if regularly performed voice recordings can be used as a diagnostic tool in order to predict the need for dilation procedures. The investigators feel that successful use of remote voice recording technology with algorithmic analysis will improve patient quality of life.

Participants needed: 100
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Johns Hopkins UniversityUpdated: Aug 6, 2025Locations: 1
Eligibility criteria

Current diagnosis of laryngotracheal stenosis [+4]

Inability to use the app associated with the study. [+2]