Health Trials

Immunosuppression After Kidney Transplantation

2

Review clinical trials related to Immunosuppression After Kidney Transplantation. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Tolerance Through Mixed Chimerism (Sip-Tego)

This is an open-label, single-institution study to assess the safety and the efficacy of the Sip-Tego regimen for the induction of donor-specific immunologic unresponsiveness to a renal allograft. The investigators propose to treat 6 adult subjects in end-stage renal disease (ESRD) who do not demonstrate evidence of prior sensitization.

Participants needed: 12
Trial details
Phase: Early Phase 1Age: 18-65Biological sex: AllType: InterventionalSponsor: Tatsuo Kawai, MD, PhDUpdated: Jun 8, 2026Locations: 1
Eligibility criteria

Male or female 18-65 years of age. [+7]

ABO blood group-incompatible renal allograft [+26]

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Status: Not yet recruiting

(TNX-1500) in Kidney Transplant Recipients

The primary objective is to investigate the safety and efficacy of TNX-1500, an FC-modified anti-CD154 mAb, in five kidney transplant recipients at 12 months.

Participants needed: 5
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Ayman Al Jurdi, MDUpdated: Feb 25, 2026Locations: 2
Eligibility criteria

Male or female subjects ≥18 to 75 years of age. [+4]

Recipient seropositive for human immunodeficiency virus (HIV-1), or hepatitis B... [+22]

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