Status: Not yet recruiting
The PICCOLETO XI A-PREP Study
To compare the angiographic and clinical outcomes of aggressive versus standard balloon preparation during drug-coated balloon (DCB) angioplasty for in-stent restenosis (ISR). The study will evaluate whether more aggressive lesion preparation with cutting/scoring/OPN balloons improves outcomes compared to standard preparation with semi-compliant or non-compliant balloons.
Participants needed: 500
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Fondazione Ricerca e Innovazione Cardiovascolare ETSUpdated: Feb 5, 2026
Eligibility criteria
Adult patients ≥18 years of age [+1]