Induction Chemotherapy

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Review clinical trials related to Induction Chemotherapy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Prognostic Impacts of Lipid Profile and BMI in Adult AML

The goal of this observational study is to evaluate the changes in lipid profile parameters (total cholesterol, triglycerides, HDL-C, and LDL-C) in adult AML patients before and after intensive induction chemotherapy. The main questions it aims to answer are: * Are there correlations between metabolic changes (in lipid profile and BMI) and treatment outcomes, including remission status and incidence of chemotherapy-related complications? * Can the baseline lipid profile and BMI serve as prognostic markers for response to induction chemotherapy.? Participants will be observed before and after induction chemotherapy regarding their lipid profile, and BMI, observing any correlations between the different results with any complications, and with remission status.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Assiut UniversityUpdated: Aug 27, 2025Locations: 1Duration: 35 Days
Eligibility criteria

Adult patients (≥18yearsold) newly diagnosed with AML. [+2]

Patients with secondary or relapsed AML. [+5]

Status: Recruiting

Induction Toripalimab and Chemotherapy in Locally Advanced Cervical Cancer

To explore the efficacy of incorporating neoadjuvant immunotherapy into neoadjuvant chemotherapy in locally advanced cervical cancer patients with high risk of recurrence.

Participants needed: 20
Trial details
Phase: Phase 1, Phase 2Age: 18-75Biological sex: FemaleType: InterventionalSponsor: Tianjin Medical University Cancer Institute and HospitalUpdated: Mar 11, 2025Locations: 1
Eligibility criteria

Untreated locally advanced cervical cancer patients with clear pathological diag... [+8]

Concomitant other malignancies; [+13]

Status: Recruiting

Envafolimab Plus Chemoradiotherapy for Locally Advanced NPC, a Prospective, Single Armed Phase II Trial.

Patients diagnosed with locally advanced nasopharyngeal carcinoma will be recruited in this study. All the patients will get 3 cycles of GP+ Envafolimab for the induction chemotherapy. After that, the patients will receive concurrent chemoradiotherapy. Radiotherapy will be given by IMRT, under the dose of GTVnx 68-70Gy/30-33f, 5d/w,6-7w, during which, every patient would receive 2 cycles of DDP+Envafolimab as concurrent chemotherapy. Then patients would receive Envafolimab every 3 weeks for maintenance treatment for a year, until disease progression or intolerance of treatment. . We aim to evaluate the three years progression free survival of these patients by the combination of Envafolimab with curative chemoradiotherapy.

Participants needed: 36
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Sun Yat-sen UniversityUpdated: Aug 10, 2022Locations: 1
Eligibility criteria

ECOG 0-1 [+5]

recurrent or metastatic NPC patients [+16]