Infant Conditions

5

Review clinical trials related to Infant Conditions. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Advanced Wireless Sensors for Neonatal Care in the Delivery Room

The goals of this observational study is to assess whether a new advanced wireless skin sensor vital sign monitoring system can effectively monitor the vital signs of healthy newborn infants (≥ 35 weeks gestational age). The main aims of this Study are to: 1. Assess feasibility 2. Evaluate safety 3. Determine accuracy of the wireless monitoring system, compared to the standard of care wired vital sign monitoring system, immediately after delivery and for the first 2h of age in the obstetrical center under unsupervised parents' care. The newborn infants participating in the Study will have both vital sign monitoring systems placed on their chest and limb. Their vital signs will be monitored for 2h consecutively.

Participants needed: 600
Trial details
Age: 35-42Biological sex: AllType: InterventionalSponsor: Guilherme Sant'Anna, MDUpdated: May 8, 2026Locations: 5
Eligibility criteria

Newborns ≥35 weeks (gestational age) [+2]

Newborns ≤ 35 weeks (gestational age) [+2]

Status: Recruiting

PK/PD of Digoxin in Infants With SVHD

The primary participant will be an infant with single ventricle heart disease. This is a research study to learn more about how the medication digoxin, which is routinely prescribed to infants and children with heart disease in pediatric cardiac intensive care units is processed by their bodies and how it may help their cardiac function. The investigators will collect blood or will collect blood samples when bloodwork is checked as part of regular care ("opportunistic"). The investigators will also collect information from medical records. Being part of this study will not change treatment plan or medications. The risks of this study include loss of confidentiality and risks associated with having blood drawn. The study team will make every effort to minimize these risks.

Participants needed: 20
Trial details
Phase: Phase 1, Phase 2Age: 30-6Biological sex: AllType: InterventionalSponsor: Duke UniversityUpdated: Jan 30, 2026Locations: 2
Eligibility criteria

Diagnosis of single ventricle congenital heart disease [+5]

Gestational age at birth <35 weeks [+7]

Status: Recruiting

Providing an Optimized and Empowered Pregnancy for You (POPPY) Aim 3: Randomized Controlled Trial

The PᵌOPPY study is designed to support the American Heart Association's mission to improve maternal/infant health outcomes and address inequities in maternal/infant health care. The P3OPPY Project is one of five projects within the American Heart Association P3 EQUATE Network. The overarching goal of the P3 EQUATE American Heart Association Health Equity Research Network (HERN) is to promote equity in Maternal and Infant Health outcomes by identifying innovative and cost-effective strategies to enhance access to quality health information, care, and experiences during pregnancy, postnatal and postpartum/preconception periods, particularly for Black and under-served populations. Collectively, the investigators will collaborate with pregnant and postpartum individuals and their families, hospitals, and communities to discover ways to reduce racism and social problems that contribute to poor health outcomes. In this trial, 400 non-Hispanic Black participants will be randomized to see if 2 promising interventions (digital health interventions and community health workers) reduce adverse pregnancy outcomes.

Participants needed: 400
Trial details
Age: 16-49Biological sex: FemaleType: InterventionalSponsor: University of Alabama at BirminghamUpdated: Aug 17, 2025Locations: 1
Eligibility criteria

Self Identifies as Non-Hispanic Black [+8]

Declines randomization [+5]

Status: Recruiting

Be Sweet to Babies During Nasolaryngoscopy

The investigators want to know if sugar water containing 24% sucrose is helpful in reducing pain in babies during scopes.

Participants needed: 60
Trial details
Age: 1-12Biological sex: AllType: InterventionalSponsor: The Hospital for Sick ChildrenUpdated: Jul 4, 2025Locations: 1
Eligibility criteria

Patient <12 months of age; [+3]

Patient >12 months of age [+15]

Status: Recruiting

Prevalence of FGIDs and Probiotics Study

This is a study to evaluate the prevalence of FGIDs in infants using the Thai version of Rome IV diagnostic questionnaire for functional gastrointestinal disorders in infants and evaluate the efficacy of Limosilactobacillus reuteri DSM 17938 to prevent FGIDs in infants.

Participants needed: 512
Trial details
Age: 3-1Biological sex: AllType: InterventionalSponsor: Chulalongkorn UniversityUpdated: Jul 2, 2025Locations: 1
Eligibility criteria

Healthy and term (GA 37-41 weeks) infants [+4]

not willing to anticipate in the study [+1]