Inguinal Hernia

26

Review clinical trials related to Inguinal Hernia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Perioperative Rehab for Inguinal Hernia Repair

Despite how common inguinal hernia repair (IHR) surgery is, there is little research on how best to prepare people for this operation. Surgeons' advice to patients about exercise and physical activity are inconsistent and usually based on their clinical opinion. Some surgeons recommend exercise to help prepare for the operation while others say to rest. Research is needed to help know whether exercise is helpful before and after IHR surgery. This study will observe the effects of education and exercise before and immediately after IHR surgery. Half of the participants will be randomized to an education and exercise group and the other half to a non-exercise, care as usual group. Participant outcomes will be measured up to 3 months after their surgery. It is expected that participants in the education and exercise group will have: 1) less pain at follow-up, 2) better hernia-related outcomes, 3) quicker return to activity and work, and 4) improved overall experience surrounding IHR surgery. This project will help in developing clear guidelines for pre- and post-operation to better prepare patients for IHR surgery.

Participants needed: 98
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of AlbertaUpdated: Jul 2, 2026Locations: 1
Eligibility criteria

scheduled to undergo first time elective inguinal hernia repair [+4]

recurrent hernia [+2]

Status: Not yet recruiting

Image-Guided Herniorrhaphy Study

This pilot clinical study will evaluate the safety and effectiveness of a new image-guided, needle-based approach for repairing abdominal or groin hernias in adults who are unable or unwilling to undergo traditional open or laparoscopic surgery. The technique uses ultrasound and, when needed, CT imaging to guide a hollow needle preloaded with barbed suture through the skin to close the hernia defect without large incisions or general anesthesia. Each participant will undergo one image-guided procedure and will be followed for eight months to assess complications and changes in hernia-related quality of life. Approximately thirty participants will be enrolled. The study aims to determine whether this minimally invasive approach is safe, feasible, and capable of improving hernia symptoms enough to justify a larger clinical trial

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of California, DavisUpdated: Jun 16, 2026Locations: 1
Eligibility criteria

English-speaking adult with reducible hernia(s) or diastasis smaller than approx... [+1]

Children, prisoners, and pregnant women (possibly requiring a pregnancy test on... [+5]

Status: Recruiting

TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair

Inguinal hernia repair remains one of the most commonly performed surgical procedures worldwide. Tension-free repair with mesh augmentation is the predominant treatment option, either achieved by preperitoneal laparoscopic hernioplasty or Lichtenstein procedure (LP). As the recurrence rate is reduced to less than 5 % after mesh repair, nowadays, long-term morbidity associated with open inguinal hernia repair is mainly related to chronic postoperative inguinal pain (CPIP). Despite many hypotheses about the possible causes for CPIP, there is now consensus that involvement of inguinal nerves plays a major role. The trans rectus sheath extra-peritoneal procedure (TREPP) is a minimally invasive open approach utilizing the rectus sheath to access the preperitoneal space. It has shown promise in providing effective repair with potential advantages in cosmesis, postoperative pain, and recurrence rates. It is a medial approach avoiding the interference with the course of all (three) inguinal nerves through lateral abdominal wall.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Assiut UniversityUpdated: Jun 1, 2026Locations: 1
Eligibility criteria

Adults with primary unilateral or bilateral inguinal hernia

Strangulated hernias. [+1]

Status: Recruiting

Pneumoperitoneum Duration and Bicarbonate Changes in Laparoscopic Hernia Surgery

The goal of this observational study is to learn how the length of pneumoperitoneum during laparoscopic inguinal hernia surgery may affect changes in blood bicarbonate levels. Pneumoperitoneum is the use of carbon dioxide gas to create space inside the abdomen during laparoscopic surgery. The main question this study aims to answer is whether a longer pneumoperitoneum time is associated with changes in blood bicarbonate levels after surgery. Participants are adults undergoing laparoscopic inguinal hernia repair as part of their routine medical care. Researchers will measure blood gas values, including bicarbonate levels, before surgery and again two hours after surgery. The change in bicarbonate levels will be compared with the duration of pneumoperitoneum during the operation. The results of this study may help improve the understanding of metabolic changes that occur during laparoscopic surgery.

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Haseki Training and Research HospitalUpdated: Mar 16, 2026Locations: 1
Eligibility criteria

Age ≥18 years [+2]

Pregnancy [+4]

Status: Recruiting

Feasibility Study of Non-Contact Imaging-Based Physiological Monitoring in the Operating Room

This study aims to evaluate the feasibility and accuracy of a non-contact, camera-based physiological monitoring technology in a perioperative setting (including anesthesia induction, surgery, and recovery).Conventional vital sign monitoring tools-such as ECG leads, blood pressure cuffs, and pulse oximeters-require direct skin contact, which may pose risks of cross-infection or skin injury in vulnerable populations (e.g., newborns or elderly patients). This research utilizes remote Photoplethysmography (rPPG) technology to estimate vital signs, including heart rate, blood pressure, and blood oxygen saturation (SpO2), by analyzing facial video captured via standard camera devices (Logitech C930, iPhone 16 Pro Max, and Samsung Galaxy S24 Ultra).The primary goal is to assess the consistency and stability of this non-contact system compared to clinical gold-standard monitors (Masimo Root, SedLine O3, and Radical-7) during actual surgical procedures. The findings will serve as a foundation for developing non-invasive, supplementary monitoring tools in dynamic clinical environments.

Participants needed: 315
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Taipei Veterans General Hospital, TaiwanUpdated: Mar 16, 2026Locations: 1Duration: 1 Day
Eligibility criteria

Patients aged >18 years. [+2]

Patients aged < 18 years. [+4]

Status: Recruiting

PRO-RSTAP: Effect of TAP and RS Blocks on Recovery After Inguinal Hernia Surgery (PRO-RSTAP)

Inguinal hernia repair is a common surgical procedure, often performed as day-case surgery. Despite standardized surgical techniques, postoperative pain may delay recovery and occasionally lead to unplanned hospital admission. The PRO-RSTAP study is a prospective, randomized, double-blind clinical trial evaluating whether ultrasound-guided transversus abdominis plane (TAP) block, rectus sheath (RS) block, or their combination improves postoperative recovery after open inguinal hernia surgery. Adult patients undergoing unilateral open inguinal hernia repair are randomized into four groups receiving either combined TAP and RS blocks, TAP block only, RS block only, or placebo blocks , in addition to standard perioperative care. The primary outcome is total perioperative opioid consumption measured as intravenous morphine equivalents. Secondary outcomes include postoperative pain scores, need for rescue analgesia, postoperative nausea and vomiting, time to discharge, unplanned hospital admission, and chronic postoperative pain during long-term follow-up. The aim of this study is to determine the individual and combined effects of TAP and RS blocks on postoperative analgesia and recovery in patients undergoing open inguinal hernia repair.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Tampere University HospitalUpdated: Feb 20, 2026Locations: 1
Eligibility criteria

Adults aged 18 years or older [+2]

Emergency surgery [+4]

Status: Recruiting

Prevention of Surgical Site Infection in Open Paediatric Groin Surgeries Using Intravenous Prophylactic Antibiotics and Antimicrobial-coated Sutures

The goal of this clinical trial is to learn if the use of prophylactic antibiotics and antimicrobial-coated sutures can prevent surgical site infection in children undergoing open groin surgeries. The main question it aims to answer is: • Does the use of intravenous prophylactic antibiotics or antimicrobial-coated sutures significantly reduce the occurrence of surgical site infection in children undergoing open groin surgeries? Researchers will compare no antibiotic use to the use of intravenous prophylactic antibiotics, or antimicrobial-coated sutures to see if the use of intravenous prophylactic antibiotics and antimicrobial-coated sutures significantly reduces the occurrence of surgical site infection following open groin surgeries in children. Participants will: * Undergo open groin surgery with either the use of intravenous prophylactic antibiotic or antimicrobial-coated sutures or without antibiotic use * Visit the clinic on postoperative days 5, 13 and 30 for review of the surgical wounds for any sign of infection.

Participants needed: 174
Trial details
Age: Up to 15Biological sex: AllType: InterventionalSponsor: Olawumi OlajideUpdated: Jan 16, 2026Locations: 1
Eligibility criteria

All patients with clinical conditions requiring daycase open groin surgery

Re-operations [+4]

Status: Recruiting

A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults

The purpose of this study is to collect data about local versus general anesthesia for inguinal hernia repair in Veterans aged 60 years for planning a larger, multisite randomized clinical trial. Approximately 80 participants will be enrolled and can expect to be on study for 6 months.

Participants needed: 80
Trial details
Age: 60+Biological sex: AllType: InterventionalSponsor: University of Wisconsin, MadisonUpdated: Jan 7, 2026Locations: 3
Eligibility criteria

Age greater than or equal to 60 years [+4]

The hernia that the patient is being evaluated for has undergone prior repair [+14]

Status: Not yet recruiting

TENS for Pain and Sleep After Hernia Surgery

This study evaluates whether Transcutaneous Electrical Nerve Stimulation (TENS) improves postoperative pain and sleep quality in adults undergoing inguinal hernia surgery. After surgery, participants will receive physician-supervised TENS or usual care. Pain intensity and sleep quality will be measured and compared between groups to assess the effectiveness and safety of TENS as a supportive recovery method.

Participants needed: 80
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Nigde Omer Halisdemir UniversityUpdated: Jan 6, 2026Locations: 1
Eligibility criteria

Adults (≥18 years) undergoing elective inguinal hernia surgery

History of epilepsy, cardiac pacemaker, or other contraindications to TENS

Status: Not yet recruiting

Comparative Study on the Post-operative Pain and Other Outcomes of Mesh Fixation With Prolene vs Vicryl vs Skin Staples in Lichtenstein Inguinal Hernia Repair.

We are going to see the outcome measures for patient and compare them across two groups, those who are undergoing mesh fixation for inguinal hernia by sutures, and those who are fixated by skin staples.

Participants needed: 132
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: King Edward Medical UniversityUpdated: Dec 17, 2025
Eligibility criteria

Patients undergoing inguinal hernia repair [+2]

COPD [+3]

Status: Not yet recruiting

A Comparison Between Two Laparoscopic Techniques in Management of Inguinal Hernias in Pediatrics

To compare between the use of the percutaneous internal ring suturing (PIRS) technique and the Laparoscopic intraperitoneal purse-string suture sac closure technique. in pediatrics \& evaluate the safety, efficacy feasibility ,operative time ,postoperative pain ,recurrence rate of both approaches.

Participants needed: 50
Trial details
Age: 1-18Biological sex: AllType: InterventionalSponsor: Assiut UniversityUpdated: May 16, 2025
Eligibility criteria

1. Age 1month to 18 years. 2. Denovo Inguinal Hernias. 3. Uncomplicated Inguinal...

1. Complicated Inguinal Hernia 2. Age more than 18 Years 3. cases inwhich laparo...

Status: Not yet recruiting

Effects of Virtual Glasses, Stress Ball and Music Intervention on Pain, Anxiety and Comfort in Patients Undergoing Inguinal Hernia Surgery

Although it changes with age, due to its high incidence and prevalence, inguinal hernia is one of the most commonly performed surgeries by general surgeons. Pain, anxiety and changes in comfort levels in patients after inguinal hernia repair surgery negatively affect the patient's recovery after surgery. One of the goals of nursing care practices in the perioperative period, especially in patients undergoing surgery, is to provide and maintain patient comfort. Today, the concept of comfort is a part of quality nursing care, allowing patients to be comfortable, carefree, recover more quickly and cope better with disease stress. Using non-pharmacological methods in pain management reduces the use of pharmacological methods, increases the patient's comfort level, reduces stress and anxiety, increases the individual's sense of control over their own health and increases physical function and daily life activities. Virtual reality, music therapy, stress ball are used in various areas of clinical medical care as a way to distract attention and relieve pain.

Participants needed: 120
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Cagla ToprakUpdated: May 11, 2025
Eligibility criteria

Between the ages of 18-70 Inguinal surgery will be performed, [+4]

• Any postoperative complications, [+2]

Status: Recruiting

Conventional Versus Robot Assisted Laparoscopic Inguinal Hernia Repair

Evaluate the early postoperative course of patients undergoing laparoscopic inguinal hernia repair with either a conventional or a robot assisted approach and with or without the injection of the trocar wounds with a local anesthetic.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Algemeen Ziekenhuis Maria MiddelaresUpdated: Apr 11, 2025Locations: 1
Eligibility criteria

adult patients presenting with a bilateral inguinal hernia planned for a minimal...

Age below 18 years [+7]

Status: Recruiting

Uterine Round Ligament Preservation Vs Resection in Laparoscopic Inguinal Hernia Repair in Women:A Multicenter,Stratified Randomized Controlled Trial

This study aims to compare the clinical effects of uterine round ligament preservation versus resection in laparoscopic inguinal hernia repair in women.The primary outcomes included Time required for patient surgery.The secondary outcomes included Inguinal hernia recurrence,quality of life assessment,Indicators of postoperative recovery,, et al.

Participants needed: 466
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Nanchong Central HospitalUpdated: Mar 25, 2025Locations: 1
Eligibility criteria

►Age : Female patients over 18 years of age without a childbearing requirement [+2]

►Combined with severe heart, liver, kidney and other diseases. [+2]

Status: Recruiting

Modified Guarnieri-Desarda Technique Versus Lichtenstein Technique in Inguinal Hernia Repair

The aim of this study is to compare the surgical outcome of both Lichnichtien tension free mesh hernioplasty of inguinal hernia and the combined modified Guarnieri Desarda technique in terms of postoperative pain, post operative complications (seroma, hematoma, wound infection), chronic inguinodenia, early recurrence and assessment of testicular vascularity and size by application of a testicular duplex and ultrasound.

Participants needed: 40
Trial details
Age: 18+Biological sex: MaleType: InterventionalSponsor: Cairo UniversityUpdated: Mar 14, 2025Locations: 1
Eligibility criteria

Adult male patients aged 18 years or older. [+2]

Patients younger than 18 years old. [+5]

Status: Recruiting

Transversalis Fascia Plane vs Ilioinguinal and Iliohypogastric Nerve Block for the Treatment of CPIP

The aim of this study was to compare the efficacy of ultrasound (US)-guided transversalis fascia plane block (TFP) and ilioinguinal (II) and iliohypogastric (IH) nerve block in the treatment of chronic post-herniorrhaphy inguinal pain (CPIP) refractory to conservative treatments. For this evaluation, a numerical rating scale (NRS) will be used before and after both interventions.

Participants needed: 80
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Diskapi Teaching and Research HospitalUpdated: Mar 12, 2025Locations: 1
Eligibility criteria

Complaints of inguinal pain >12 weeks post-herniorrhaphy surgery [+2]

Other causes of inguinal pain (haematoma, infection, tubo-ovarian disease, absce... [+3]

Status: Recruiting

Chronic Pelvic Pain in Females and Males

Pelvic pain is under-reported in healthy adults. Many patients with pelvic pain under-estimate the problem. Chronic pelvic pain can be managed properly, if diagnosed promptly. This is a quantitative analysis of prospective clinical data. It evaluates the management of pelvic pain in a cohort population, and analyzes the treatment outcome.

Participants needed: 1,000
Trial details
Age: 20-99Biological sex: AllType: ObservationalSponsor: Salem Anaesthesia Pain ClinicUpdated: Jan 27, 2025Locations: 1
Eligibility criteria

Patients with chronic pelvic pain [+4]

Patients with spinal pain [+1]

Status: Recruiting

The Importance of Preserving the Round Ligament in the Repair of Inguinal Hernias in Women

The aim of this study is to evaluate the impact of preserving or not preserving the round ligament during laparoscopic Trans Abdominal Pre-Peritoneal (TAPP) hernia repair on postoperative outcomes in female patients. Specifically, the study will compare outcomes such as postoperative pain, seroma, hematoma, prolapsus of uterina , recurrence rates, and quality of life between patients whose round ligament was preserved versus those whose ligament was cut.

Participants needed: 106
Trial details
Age: 18-70Biological sex: FemaleType: InterventionalSponsor: Muhammet Mustafa VuralUpdated: Jan 22, 2025Locations: 1
Eligibility criteria

Age Range: Female patients aged between 18 and 70 years. [+5]

Age: Female patients under 18 years old or over 70 years old. [+5]

Status: Recruiting

SetUp Study for HugoTM RAS Inguinal Hernia Repair

The goal of this observational cohort study is to evaluate the evolution of the operative time in performing robotic assisted laparoscopic inguinal hernia repair (rTAPP) during the learning curve of the first 50 patients using the HugoTM Ras (Medtronic) robotic system using the setup guide. Researchers will compare to the operative time for rTAPP of 50 patients by the same surgeon in another hospital using the daVinci Xi (Intuitive Surgical) robotic system.

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Algemeen Ziekenhuis Maria MiddelaresUpdated: Sep 19, 2024Locations: 2
Eligibility criteria

Recurrent hernias after previous preperitoneal mesh placement. [+5]

Status: Recruiting

Factors Influencing the Results of Treatment in Patients With Hernias of Various Localizations

The study attempts to quantify the relative risks for acute postoperative pain, complications rate, chronic postoperative pain (CPIP) and recurrence rate after different methods of repair of groin, umbilical and incisional hernia depending on surgical technique, mesh type and fixation suture material. For this purpose the investigators will analyze data from the Kalinigrad Hernia Registry (KHR).

Participants needed: 4,000
Trial details
Age: 18-90Biological sex: AllType: ObservationalSponsor: Immanuel Kant Baltic Federal UniversityUpdated: Jul 23, 2024Locations: 1
Eligibility criteria

All mesh and non-mesh repairs that have been registered in the KHR from January...

Patients not having a 11-digit state-assigned Personal insurance policy number. [+2]

Status: Recruiting

Repair of Inguinal Hernia

The aim of this study is to compare the outcomes of open versus laparoscopic approaches for inguinal hernia surgery and provide evidence-based guidance to the selection of the most appropriate operative technique.

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Sohag UniversityUpdated: Jul 23, 2024Locations: 1
Eligibility criteria

Emergency procedures . [+8]

Status: Recruiting

Flemish Inguinal and Femoral Hernia Prospective Registry

Prospective registry. The purpose of this clinical trial will be to measure surgical outcome parameters (e.g. recurrence, chronic pain and other quality indicators) after inguinal hernia repair using Patient Reported Outcome Measures (PROMs) in the short- and long-term.

Participants needed: 560
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Universitaire Ziekenhuizen KU LeuvenUpdated: Jul 1, 2024Locations: 2Duration: 5 Years
Eligibility criteria

Consecutively all patients with a groin hernia (inguinal and/or femoral hernia)... [+7]

Younger than 18 years [+3]

Status: Recruiting

The (Cost-) Effectiveness of Paediatric Laparoscopic Hernia Repair Compared to Open Hernia Repair

This study assess the (cost-)effectiveness of open versus laparoscopic Percutaneous Inguinal Ring Suturing (PIRS) technique for unilateral inguinal hernia repair in children aged 0-16 years.

Participants needed: 464
Trial details
Age: 0-16Biological sex: AllType: InterventionalSponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Updated: Jun 11, 2024Locations: 9
Eligibility criteria

incarcerated inguinal hernia, which have to be operated immediately, [+4]

Status: Not yet recruiting

Task Sharing in InGuinal hErnia Repair Between Surgeons and Non-surgeon Physicians

TIGER is a multicentre, 2-arm, parallel group, assessor blinded, non-inferiority randomised controlled trial with an internal pilot to assess if non-surgeon physicians (NSPs) can effectively perform mesh inguinal hernia repair compared to fully trained surgeons in adult patients with non-complicated inguinal hernia.

Participants needed: 1,782
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: University of BirminghamUpdated: May 30, 2024
Eligibility criteria

Patients older than <18 years> (male or female) and less or equal to 60 years [+3]

Complex inguinal hernias: recurrent, obstructive, or femoral hernias [+3]

Status: Not yet recruiting

Mesh Fixation Versus Non Fixation in Laparoscopic Inguinal Hernioplasty

Inguinal hernia is one of the most common types of abdominal hernias. Laparoscopic hernioplasty of inguinal hernia is a good alternative to traditional open repairs even in simple unilateral primary inguinal hernia in terms of decrease post operative pain and complications with comparable recurrence rates.Two techniques are described in laparoscopic hernioplasty and have been extensively studied in randomised trials. The totally extraperitoneal (TEP) approach is more widely used than the transabdominal preperitoneal (TAPP) approach. In this study we will compare between the results of mesh fixation and non fixation as regard operative and postoperative data.

Participants needed: 30
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Assiut UniversityUpdated: Feb 14, 2024
Eligibility criteria

Any male or female above 18 years old that has uncomplicated inguinal hernia

Patients with contraindications to use laparoscopy as cardiac or immunocompromis... [+1]