Inguinal Hernia Repair

9

Review clinical trials related to Inguinal Hernia Repair. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Comparison of Laryngeal Mask Airway Versus Endotracheal Intubation in Pediatric Laparoscopic Inguinal Hernia Repair

Inguinal hernia is one of the most common conditions requiring surgical intervention in childhood, with a reported lifetime prevalence of 1-4%. With the increasing use of minimally invasive techniques such as PIRS (Percutaneous Internal Ring Suturing) among laparoscopic surgical procedures, perioperative anesthesia and airway management have become a critical area of clinical decision-making. The traditional approach in pediatric laparoscopic surgery is endotracheal intubation (ETT). Although ETT provides reliable airway control, it carries certain disadvantages. In contrast, the laryngeal mask airway (LMA) is less invasive and is associated with faster recovery. Systematic reviews and meta-analyses conducted in recent years have shown that the LMA may be safe for ventilation in pediatric laparoscopy, reduces peak airway pressure, and shortens recovery time. No well-designed, multicenter study with an adequate sample size comparing the LMA and ETT in pediatric laparoscopic inguinal hernia surgery has yet been conducted. This gap limits evidence-based decision-making in a clinical setting that directly impacts practice. Therefore, the aim of this study is to compare LMA and ETT in pediatric laparoscopic inguinal hernia repair. In this regard, the study is unique and necessary from both clinical and academic perspectives for determining the optimal airway strategy in pediatric laparoscopy.

Participants needed: 266
Trial details
Age: 1-10Biological sex: AllType: InterventionalSponsor: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research HospitalUpdated: Jun 24, 2026Locations: 1
Eligibility criteria

being between 1 and 10 years of age, [+3]

Obesity (body weight >95th percentile), [+8]

Status: Recruiting

TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair

Inguinal hernia repair remains one of the most commonly performed surgical procedures worldwide. Tension-free repair with mesh augmentation is the predominant treatment option, either achieved by preperitoneal laparoscopic hernioplasty or Lichtenstein procedure (LP). As the recurrence rate is reduced to less than 5 % after mesh repair, nowadays, long-term morbidity associated with open inguinal hernia repair is mainly related to chronic postoperative inguinal pain (CPIP). Despite many hypotheses about the possible causes for CPIP, there is now consensus that involvement of inguinal nerves plays a major role. The trans rectus sheath extra-peritoneal procedure (TREPP) is a minimally invasive open approach utilizing the rectus sheath to access the preperitoneal space. It has shown promise in providing effective repair with potential advantages in cosmesis, postoperative pain, and recurrence rates. It is a medial approach avoiding the interference with the course of all (three) inguinal nerves through lateral abdominal wall.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Assiut UniversityUpdated: Jun 1, 2026Locations: 1
Eligibility criteria

Adults with primary unilateral or bilateral inguinal hernia

Strangulated hernias. [+1]

Status: Not yet recruiting

Perioperative Safety and Long-Term Outcomes of Mesh Repair in Nonagenarians Undergoing Elective Inguinal Hernia Repair

To evaluate the clinical characteristics, postoperative outcomes, and factors associated with Clavien-Dindo grade ≥II complications in nonagenarians undergoing elective inguinal hernia repair. Preoperative, intraoperative, and postoperative data of nonagenarians who underwent elective inguinal hernia repair were collected. The primary outcome was Clavien-Dindo grade ≥II complications. Univariable logistic regression was used to identify associated factors.

Participants needed: 150
Trial details
Age: 90+Biological sex: AllType: ObservationalSponsor: Fudan UniversityUpdated: May 22, 2026
Eligibility criteria

Not listed

Status: Recruiting

De-Implementation of Low-value Testing in Patients Undergoing Low-Risk Surgery

This trial aims to evaluate the effectiveness of a multi-level, multi-component de-implementation strategy to reduce unnecessary preoperative testing. Sixteen Michigan Value Collaborative (MVC)/Michigan Surgical Quality Collaborative (MSQC) sites in Michigan will implement several tools that have been proven to reduce unnecessary testing at a single site, including clinician education, a decision aid, audit and feedback on performance, and a pay-for-performance incentive. The researchers believe that, through the use of these strategies, there will be a significant reduction in unnecessary preoperative testing during the intervention.

Participants needed: 16
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of MichiganUpdated: May 8, 2026Locations: 1
Eligibility criteria

Over 30% of testing rates on at least one of the three index procedures (breast...

none

Status: Not yet recruiting

Mesh Infection After Hernioplasty: Complete vs Partial Removal - Retrospective Study on Outcomes and Pathogen Analysis

Background: Mesh infection after tension-free inguinal hernia repair (IHR) is rare and challenging. When conservative treatment fails, surgery is often required. This study compared clinical outcomes of complete versus partial mesh removal in affected patients. Materials and Methods: We retrospectively analyzed patients who underwent surgery for mesh infection after IHR in our hospital between January 2016 and December 2025. Baseline data, perioperative indicators, postoperative complications, and microbiological results were compared between the complete and partial removal groups.

Participants needed: 100
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Fudan UniversityUpdated: Mar 24, 2026
Eligibility criteria

Patients who underwent tension-free inguinal hernioplasty with mesh placement. [+3]

Patients with mesh infection managed conservatively (without surgical removal). [+3]

Status: Recruiting

Visually Guided TAP Block in Laparoscopic TAPP Hernia Repair

This prospective, randomized clinical study aims to evaluate the effectiveness of the Transversus Abdominis Plane (TAP) block performed under direct laparoscopic vision in reducing postoperative pain and improving recovery after laparoscopic inguinal hernia repair using the TAPP (Transabdominal Preperitoneal) technique. The study will enroll 100 adult patients undergoing elective laparoscopic TAPP hernia repair at the University Clinical Hospital in Olsztyn, Poland. Participants will be randomly assigned to two equal groups. In the study group, a bilateral TAP block will be performed under direct vision using 20 ml of 0.25% bupivacaine on each side after establishing pneumoperitoneum. The control group will undergo the same surgical procedure without the TAP block. All patients will receive standardized anesthesia and postoperative pain management according to hospital protocol. Postoperative pain intensity will be assessed using the Visual Analogue Scale (VAS) at 0, 6, and 12 hours after surgery. Additional data, such as time to mobilization, use of rescue analgesics, and occurrence of postoperative complications (hematoma, swelling, subcutaneous emphysema, transient muscle weakness), will also be recorded. The primary goal of this study is to determine whether a laparoscopically guided TAP block can effectively reduce postoperative pain and improve recovery parameters following TAPP hernia repair. The results may help establish a simple, safe, and reproducible method of multimodal analgesia in minimally invasive inguinal hernia surgery.

Participants needed: 100
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: University of Warmia and Mazury in OlsztynUpdated: Mar 17, 2026Locations: 1
Eligibility criteria

Age 18-80 years [+4]

Recurrent or strangulated inguinal hernia [+7]

Status: Recruiting

Robotic Minimally Invasive Inguinal Hernia Repair Post-Market Clinical Study With the DEXTER Robotic System

The purpose of this post-market, observational study is to collect data under anticipated conditions of use that demonstrates that DEXTER performs as intended in the intended patient population, including a variety of representative disease etiologies and demographic groups.

Participants needed: 140
Trial details
Age: 22+Biological sex: AllType: ObservationalSponsor: Distalmotion SAUpdated: Jan 22, 2026Locations: 2
Eligibility criteria

Subject is ≥ 22 years of age at time of enrollment/consent [+2]

Subject with any relative and absolute contraindications for the use of conventi... [+2]

Status: Not yet recruiting

Modified vs. Conventional Laparoscopic TAPP for Inguinal Hernia

This study aims to compare the outcomes of two laparoscopic techniques for repairing inguinal hernias: the modified tumescent technique (MT-TAPP) and the conventional laparoscopic transabdominal preperitoneal technique (CL-TAPP). The primary goal is to determine which technique provides better outcomes in terms of operative time, ease of pre-peritoneal space dissection, postoperative pain, and the formation of seromas. The study will involve 60 patients diagnosed with unilateral inguinal hernias, randomly assigned to either group. Participants in Group A will undergo the MT-TAPP procedure, which involves pre-peritoneal infiltration of a local anesthetic solution to improve dissection and reduce pain. Group B will undergo the standard CL-TAPP procedure. Data will be collected on various outcome measures and analyzed to identify which technique leads to quicker recovery, less postoperative pain, and fewer complications. The results of this study will help guide surgical decisions and improve patient outcomes in inguinal hernia repair.

Participants needed: 60
Trial details
Age: 18-50Biological sex: AllType: InterventionalSponsor: University of Health Sciences LahoreUpdated: Jan 28, 2026
Eligibility criteria

Age: 18 to 50 years. [+4]

Femoral Hernias. [+7]

Status: Recruiting

Comparison of Outcomes of Hernia Sac Transection and Sac Reduction in Open Pediatric Inguinal Hernia Repair in Ramathibodi Hospital

The goal of this clinical trial is to learn if hernia sac transection works to treat pediatric inguinal hernia. Researchers will compare hernia sac transection to hernia sac reduction (traditional inguinal hernia repair) to see outcome in 6 months. Visit the clinic at week1, month3, month 6 for follow-up.

Participants needed: 40
Trial details
Age: 1-18Biological sex: MaleType: InterventionalSponsor: Piyanuch LormuangthongUpdated: Nov 28, 2025Locations: 1
Eligibility criteria

Male pediatric patients under 18 years old [+3]

Preterm infants [+4]