Inherited Retinal Degeneration

2

Review clinical trials related to Inherited Retinal Degeneration. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

This is an international, multicenter study with two components: Registry * A standardized genetic screening and a prospective, standardized, cross-sectional clinical data collection * Enrollment is open to all genes on the RD Rare Gene List Natural History Study * A prospective, standardized, longitudinal Natural History Study * Enrollment opens gene-by-gene, based on funding and within-gene Registry enrollment The study objectives are as follows. Registry Objectives 1. Genotype Characterization 2. Cross-Sectional Phenotype Characterization (within gene) 3. Establish a Link to My Retina Tracker Registry (MRTR) 4. Ancillary Exploratory Studies - Pooling of Genes Natural History Study Objectives 1. Natural History (within gene) 2. Structure-Function Relationship (within gene) 3. Risk Factors for Progression (within gene) 4. Ancillary Exploratory Studies - Pooling of Genes

Participants needed: 1,500
Trial details
Age: 4+Biological sex: AllType: ObservationalSponsor: Jaeb Center for Health ResearchUpdated: Jun 26, 2026Locations: 36
Eligibility criteria

Willing to participate in the study and able to communicate consent during the c... [+8]

Current vitreous hemorrhage [+5]

Status: Recruiting

Restoration of Central Vision With PRIMA in Patients With Photoreceptor Degeneration

The objective of this study is to evaluate the efficacy and safety of the PRIMA Products in participants with inherited retinal degeneration affecting the macula (including but not limited to Stargardt disease, and Retinitis Pigmentosa). Eligible participants will be implanted with the PRIMA Stim implant. The participants will be assessed with various visual function and functional vision tests at defined timepoints throughout the clinical investigation with the PRIMA Products. The purpose of this study is to gather enough clinical data to support the clinical evaluation required for the continuous development to improve the PRIMA Products.

Participants needed: 5
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Science CorporationUpdated: Apr 2, 2026Locations: 1
Eligibility criteria

Is 18 years or older at the date of inclusion; [+5]

1. Has cataract in the study eye (with LOCS III scale NO, NC, C or P>1); (these... [+33]