Health Trials

Inherited Retinal Dystrophy

3

Review clinical trials related to Inherited Retinal Dystrophy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Safety and Efficacy Study of PUMCH-E111 Injection in Subjects With RLBP1 Related Inherited Retinal Dystrophy

The goal of this clinical trial is to evaluate the safety and efficacy of PUMCH-E111 injection in subjects with RLBP1 related Inherited Retinal Dystrophy.

Participants needed: 6
Trial details
Phase: Early Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: Peking Union Medical College HospitalUpdated: Jun 18, 2026Locations: 1
Eligibility criteria

Subjects voluntarily participate and sign the informed consent form; [+4]

Opacity of refractive media or inability to dilate pupils in the study eye that... [+24]

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Status: Not yet recruiting

A Multicenter, Randomized, Double-Blind, Controlled Clinical Study of Minocycline for the Treatment of Retinitis Pigmentosa

This is a multicenter, double-blind, randomized controlled clinical trial to get high - level evidence on minocycline's efficacy and safety（100mg/d, 200mg/d) for Retinitis pigmentosa and to find the optimal treatment dose.

Participants needed: 126
Trial details
Phase: Phase 3Age: 18-60Biological sex: AllType: InterventionalSponsor: Zhongshan Ophthalmic Center, Sun Yat-sen UniversityUpdated: Jul 24, 2025Locations: 1
Eligibility criteria

Age should be between 18 and 60 years old. [+3]

Allergic to tetracycline antibiotics. [+9]

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Status: Recruiting

Micropulsed Laser in Patients With Macular Oedema in Retinal Dystrophies

The purpose of this study is to investigate whether subthreshold treatment with micropulsed laser can be effective in resolving macular edema in patients with inherited retinal dystrophy. Visits will be performed after 1, 3, 6, 9, 12, 18, and 24 months after treatment. Laser treatment will be performed on the day of the first visit, and its repetition at subsequent visits between months 3 and 12 will be evaluated. Evaluations of treatment effects will include: * comprehensive ophthalmologic examination * multifocal electroretinogram * OCT examination * OCT-angiography examination * retinography Primary endpoint. \- central retinal thickness, measured by OCT

Participants needed: 10
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Fondazione G.B. Bietti, IRCCSUpdated: Feb 28, 2025Locations: 1
Eligibility criteria

Patients with inherited retinal disease [+8]

Patients with cataract extraction prior to 6 months [+7]

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