Injection Pain Prevention

3

Review clinical trials related to Injection Pain Prevention. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Traction, Pressure, and Rapid Muscle Release (TPR) Technique During Intramuscular Injection: Effects on Pain and Patient Satisfaction

This study will be conducted to evaluate the effect of the Traction, Pressure, and Rapid Muscle Release (TPR) technique, an innovative method used during intramuscular vitamin B12 (cyanocobalamin) injections, on patients' pain and satisfaction levels compared with the conventional injection method.

Participants needed: 102
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Bezmialem Vakif UniversityUpdated: Mar 30, 2026Locations: 1
Eligibility criteria

Voluntary participation in the study [+4]

Presence of a scar, burn, redness, hematoma, bruising, tenderness, or induration... [+7]

Status: Not yet recruiting

Nonpharmacological Management of Pain and Fear During Hormone Injection in Breast Cancer Patients

This randomized controlled study will compare the effects of the ShotBlocker device and the Helfer Skin Tap Technique on pain and fear during intramuscular hormone injections in premenopausal and postmenopausal breast cancer patients. Ninety-nine participants will be randomly assigned to three groups (ShotBlocker, Helfer, control). All injections will be administered by the same nurse using standardized procedures. Pain will be assessed with the Visual Analog Scale, and fear with the Injection Fear Scale. The study aims to identify effective nonpharmacological methods to enhance patient comfort, support treatment adherence, and improve nursing care quality.

Participants needed: 99
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Inonu UniversityUpdated: Feb 13, 2026Locations: 1
Eligibility criteria

Patients aged between 18 and 65 years. [+3]

History of chronic pain disorders, neuropathic pain syndrome, or any disease req... [+2]

Status: Recruiting

Does Ethyl Chloride Spray Work?

A procedure frequently performed by orthopaedic providers is the administration of corticosteroid injections for the management of various soft tissues and joint-related conditions, such as osteoarthritis, tendinitis, carpal tunnel syndrome, trigger finger, and de Quervain's tenosynovitis. While these injections have demonstrated effectiveness in alleviating symptoms, the discomfort associated with the procedure can be a source of anxiety and apprehension for patients. This discomfort arises from the sensation of the needle entering the affected area and the burning sensation induced by the corticosteroid solution.

Participants needed: 300
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of ChicagoUpdated: Oct 16, 2025Locations: 1
Eligibility criteria

18 years and older [+1]

Patients with previous injection experiences