Intermediate AMD

3

Review clinical trials related to Intermediate AMD. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

MacuTherm Performance Study in Patients With iAMD

The goal of this study is to demonstrate that photothermal therapy with the individually dosed treatment plan proposed by Macula Explorer delivered safely by Navilas® Laser System effectively improves the life of photoreceptors and reduces the progression of intermediate Age-related Macular Degeneration (iAMD) and preserves photoreceptors shown by Ellipsoid Zone Integrity (EZI). Participants will be randomized to either Treatment or Control Group. There will be 12 visits, monthly for the first 3 months, then quarterly until the end of the study after 2 years.

Participants needed: 240
Trial details
Age: 60-90Biological sex: AllType: InterventionalSponsor: OD-OS MacuTherm GmbHUpdated: Jun 4, 2026Locations: 4
Eligibility criteria

Male, female, or diverse [+9]

Presence of late-stage AMD, neovascular (nAMD, active or fibrotic) or geographic... [+17]

Status: Recruiting

Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration

The goal of this clinical trial is to characterize the safety and effectiveness of the i-Lumen AMD transpalpebral microcurrent device and therapy in patients with intermediate to advanced nonexudative AMD. Participants will: * Undergo an initial loading regimen, followed by 7 maintenance over the course of 11 months. * Participants will return monthly through Month 14 (3 months post-last treatment) for evaluation and monitoring.

Participants needed: 100
Trial details
Age: 60+Biological sex: AllType: InterventionalSponsor: i-Lumen Scientific AUS PTY LTDUpdated: May 4, 2026Locations: 13
Eligibility criteria

Presence of at least one large druse >125 microns in diameter due to AMD. [+1]

Any implanted electrical device(s) including deep brain stimulator, hearing or v... [+17]

Status: Recruiting

A Clinical Trial Evaluating the Safety and Efficacy of a New Light Combination Therapy Addressing Intermediate AMD

The proposed clinical investigation wants primary to validate the safety of the innovative light therapy approach and in second priority provide insight and confirmations on therapeutic effect. By combining two clinically standard laser-light treatment, both exhibiting a solid-safe profile: the photothermal and the photobiological techniques; the investigational device (reSEES) wants to explore a completely new therapeutic approach by synergically take advantage of the inherent and already observed clinical performances of the two independent techniques.

Participants needed: 30
Trial details
Age: 50+Biological sex: AllType: InterventionalSponsor: Oculox Technologies SAUpdated: Nov 15, 2024Locations: 1
Eligibility criteria

Male and female patients ≥ 50 years of age [+3]

Myopia > 8D [+13]