Internal Hemorrhoid

3

Review clinical trials related to Internal Hemorrhoid. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Outcomes and Quality of Life Following Rectal Artery Embolization for Bleeding Internal Hemorrhoids

This study will assess how effective and safe rectal artery embolization works to treat symptomatic bleeding predominant internal hemorrhoids.

Participants needed: 20
Trial details
Age: 18-90Biological sex: AllType: ObservationalSponsor: Mayo ClinicUpdated: Jun 17, 2026Locations: 1
Eligibility criteria

Grade II or III hemorrhoidal disease as determined by a board-certified colorect... [+5]

Prior hemorrhoid surgery. [+9]

Status: Recruiting

Prospective HemorrhoIdaL EmboliSation (PILES) Registry

The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of hemorrhoid artery embolization (HAE) for symptomatic bleeding internal hemorrhoids in adults aged 18 years or older that have not responded to medical therapy. The main question it aims to answer are: 1\) Does HAE lead to sustained improvement in bleeding (HDSS scores over 12-36 months? Participants will: * Undergo HAE as part of their routine clinical care. * Complete clinical follow-up assessments at 1, 3, 6, 12, 18, 24, and 36 months after treatment, including symptom and quality-of-life questionnaires. * Have safety outcomes tracked according to Society of Interventional Radiology guidelines. There is no comparison group; results will be analyzed to identify predictors of success and inform best practices for patient selection and treatment.

Participants needed: 1,200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Joint & Vascular InstituteUpdated: Jun 12, 2026Locations: 1Duration: 5 Years
Eligibility criteria

Adults (≥18 years) with symptomatic bleeding internal hemorrhoids refractory to...

Pregnancy, coagulopathy, severe comorbidities, or inability to consent.

Status: Recruiting

CAES for Internal Hemorrhoids and Rectal Prolapse

Cap-assisted endoscopic sclerotherapy (CAES) is a new interventional therapy for internal hemorrhoids and rectal prolapse under colonoscopy. However, the long-term efficacy and safety of CAES in the treatment of internal hemorrhoids and rectal prolapse are still not clear due to the lack of large sample studies. Therefore, a nationwide multi-center, large sample, prospective and cohort study was designed to evaluate the efficacy and safety of CAES in the treatment of internal hemorrhoids and rectal prolapse, to provide reliable evidence for popularization of this minimally invasive technology.

Participants needed: 10,000
Trial details
Biological sex: AllType: ObservationalSponsor: Faming ZhangUpdated: Apr 2, 2024Locations: 1
Eligibility criteria

Grade I-III internal hemorrhoids (with or without external hemorrhoids) or/and r... [+1]

History of anoscopic/endoscopic sclerotherapy. [+11]