Interscalene Block

5

Review clinical trials related to Interscalene Block. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

The Effect of Intravenous Dexketoprofen on the Severity and Incidence of Rebound Pain

Orthopedic shoulder surgeries are associated with severe postoperative pain, particularly within the first 24-48 hours after surgery. In postoperative pain management, single or continue interscalene brachial plexus blocks, acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), and opioids administered as needed are commonly used as components of multimodal analgesia. Rebound pain is defined as severe postoperative pain (VAS ≥ 7) occurring within the first 24 hours after resolution of the block. It is considered an adverse effect of regional anesthesia and typically develops 8-12 hours after a single-shot nerve block. Risk factors for rebound pain include pre-existing pain, female sex, younger age, bone surgery, lack of intraoperative dexamethasone administration, and inadequate analgesia. The primary objective of this study is to evaluate the effect of intravenous dexketoprofen administered during the postoperative period on the incidence and severity of rebound pain in patients undergoing shoulder surgery with interscalene brachial plexus block

Participants needed: 66
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Eskisehir Osmangazi UniversityUpdated: Jun 12, 2026Locations: 1
Eligibility criteria

Not listed

Status: Recruiting

Comparison Of The Effects Of Regional Anesthesia On Brain And Carotid Artery Oxygenation In Shoulder Surgery

The aim of our study was to compare the effects of interscalene block alone and the combination of interscalene block and superficial cervical block on cerebral oxygenation, carotid artery diameter, intraoperative hemodynamics, laboratory parameters, clinical course and postoperative pain in patients undergoing shoulder surgery.

Participants needed: 70
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Sanliurfa Mehmet Akif Inan Education and Research HospitalUpdated: Mar 24, 2026Locations: 1
Eligibility criteria

18-65 years patient [+1]

Age < 18 years or > 65 years [+8]

Status: Recruiting

Interscalene Block Versus Anterior Suprascapular Block for Post-Thoracotomy Shoulder Pain

This study aims to compare the frequency of occurrence of ipsilateral shoulder pain in patients undergoing thoracotomy with ultrasound-guided interscalene block, anterior suprascapular block as adjunct to epidural and epidural block only.

Participants needed: 75
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: National Cancer Institute, EgyptUpdated: Feb 24, 2026Locations: 1
Eligibility criteria

Age > 18 years and ≤ 65 years old. [+3]

Allergy to local anesthetics. [+7]

Status: Not yet recruiting

Effect of Local Anesthetic Concentration on Rebound Pain: A Randomized Control Study

Randomized control study that compares different concentrations of local anesthetic to investigate whether a lower concentration of local anesthetic would contribute to lower rebound pain scores at 24 hours post op in patients undergoing anatomic or reverse total shoulder arthroplasty.

Participants needed: 168
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: University of VirginiaUpdated: Aug 28, 2025Locations: 1
Eligibility criteria

Total shoulder replacement patients (anatomic and reverse) [+3]

substance/opioid use disorder [+18]

Status: Recruiting

Ultrasound Guided Interscalene, Suprascapular and Anterior Glenoid Nerve Blocks on Diaphragmatic Excursion and Analgesia Following Arthroscopic Shoulder Surgery

This study aims to evaluate the diaphragmatic movement and postoperative analgesia following anterior glenoid, suprascapular, and interscalene nerve blocks in patients undergoing elective arthroscopic shoulder surgery.

Participants needed: 80
Trial details
Age: 21-65Biological sex: AllType: InterventionalSponsor: Tanta UniversityUpdated: Jul 29, 2025Locations: 1
Eligibility criteria

Age from 21 to 65 years. [+3]

Patient's refusal to participate. [+7]