Intrauterine Devices

1

Review clinical trials related to Intrauterine Devices. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Methoxyflurane for IUD Insertion and Endometrial Biopsy

The aim of this study is to determine if 3ml of inhaled Methoxyflurane, in the form of a Penthrox inhaler, reduces pain during IUD insertion and/or endometrial biopsy. The proposed study is a double-blind, placebo-controlled RCT. Each participant will be randomly assigned to one of two arms: 1. Intervention (3ml of Methoxyflurane via a Penthrox inhaler) 2. Placebo (3ml of normal saline via an identical placebo Penthrox inhaler) The primary outcome is global pain score, which will be patient-reported by the 100 mm Visual Analogue Scale (VAS) 5-minutes following the procedure (endometrial biopsy or IUD insertion).

Participants needed: 174
Trial details
Age: 18-65Biological sex: FemaleType: InterventionalSponsor: Mount Sinai Hospital, CanadaUpdated: Jul 30, 2025Locations: 1
Eligibility criteria

Any participant ≥18 years and ≤ 65 years presenting for an IUD insertion or endo... [+3]

Use of pain medication that is not an NSAID or acetaminophen (e.g. opioids, benz... [+9]