Irritable Bowel Syndrome With Diarrhea

4

Review clinical trials related to Irritable Bowel Syndrome With Diarrhea. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Effects of the Multispecies Probiotic Ecologic Barrier in IBS Patients With Upper GI Symptoms and Anxiety, Depression, or Stress

The aim of this clinical trial is to find out whether Ecologic Barrier is effective in supporting the treatment of irritable bowel syndrome (IBS) in adults. The main questions that this trial aims to answer are: * Does Ecologic Barrier help improve IBS severity when added to standard IBS treatment? * Does Ecologic Barrier help improve symptoms of anxiety, depression, and stress in patients with IBS? * Does Ecologic Barrier help improve upper gastrointestinal symptoms when added to standard IBS treatment? * What adverse events may occur when using Ecologic Barrier? The researchers will compare a group receiving standard symptom-based treatment with another group receiving standard treatment plus Ecologic Barrier. Participants will: * Receive IBS treatment for 2 months, with Ecologic Barrier added during either the first month or the second month, depending on random assignment. * Attend a follow-up visit after 1 month of treatment. * Take part in interviews about IBS severity, symptom improvement, adverse events, and symptoms of depression and anxiety at baseline, 2 weeks, 4 weeks, 8 weeks, and 12 weeks.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Institute of Gastroenterology and Hepatology, VietnamUpdated: Jun 18, 2026Locations: 1
Eligibility criteria

Indication for upper endoscopy and colonoscopy; [+3]

Positive for Helicobacter pylori by rapid urease test during endoscopy or by 13C... [+6]

Status: Recruiting

A Study to Evaluate the Efficacy and Safety of Live SK08 Powder in Patients With IBS-D

The purpose of this study is to evaluate the efficacy and safety of Live SK08 Powder compared with placebo in the treatment of participants with irritable bowel syndrome with diarrhea.

Participants needed: 1,298
Trial details
Phase: Phase 3Age: 18-70Biological sex: AllType: InterventionalSponsor: Guangzhou Zhiyi Biotechnology Co., Ltd.Updated: Apr 3, 2025Locations: 2
Eligibility criteria

1.Voluntarily sign informed consent, be able to comply with the protocol and be... [+8]

1. Patients with constipated, mixed and amorphous IBS. [+18]

Status: Recruiting

B.Subtilis Attenuate Symptoms in Diarrhea-predominant Irritable Bowel Syndrome by Increasing Hypoxanthine Biosynthesis

This is a prospective, single-blind, randomized parallel study to investigate whether B. subtilis could improve clinical symptoms of IBS-D patients. Patients are randomly assigned by envelope method. A senior gastroenterologist is responsible for prescribing medication. Researchers are blind to patients' medication. Participants with IBS are recruited and randomized to receive a 4-week administration of B. subtilis-based probiotics. Clinical symptoms and stool samples are collected before and after the trial.

Participants needed: 180
Trial details
Phase: Early Phase 1Age: 16-80Biological sex: AllType: InterventionalSponsor: Jinling Hospital, ChinaUpdated: Sep 25, 2024Locations: 2
Eligibility criteria

Not listed

Status: Not yet recruiting

Efficacy and Safety of FMT for the Treatment of IBS-D and Mental Health Comorbidity in Young Adults

The purpose of this study is to evaluate the efficacy and safety of Fecal Microbiota Transplantation compared with placebo in the treatment of Irritable Bowel Syndrome With Diarrhea (IBS-D) and Mental Health Comorbidity in Young Adults.

Participants needed: 88
Trial details
Phase: Phase 2Age: 18-29Biological sex: AllType: InterventionalSponsor: Shenzhen Hospital of Southern Medical UniversityUpdated: Jul 16, 2024Locations: 1
Eligibility criteria

Voluntarily sign informed consent, be able to comply with the protocol and be ab... [+5]

Patients with constipated, mixed and amorphous IBS. [+18]