Knee Disease

3

Review clinical trials related to Knee Disease. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Persona Revision Knee System Outcomes

The study will evaluate the performance, clinical benefits and safety of the Persona Revision Knee System in patients who have received primary or revision total knee arthroplasty (TKA) treatment. This will be done using a multicenter, single-arm, consecutive series, retrospective cohort study with prospective follow-up.

Participants needed: 380
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Zimmer BiometUpdated: Oct 24, 2025Locations: 16
Eligibility criteria

Male or female of at least 18 years of age at the time of screening. [+8]

An ulcer of the skin [+2]

Status: Recruiting

Prospective Functional, Gait, and Outcome Comparison Study of Medial Pivot Versus Single Radius Design for Total Knee Arthroplasty

Patients with degenerative joint disease can effectively be treated with a primary total knee replacement to reduce pain and improve function in their daily lives. Theoretically, achievement of normal knee motion using a medial pivot design in total knee replacements can be recreated in comparison to single radius designs, which could lead to an improvement in post-surgical outcomes and satisfaction with the procedure. The aim of this study is to compare two types of implant designs (medial pivot and single radius) in a total knee replacement using clinical outcomes, patient reported outcomes, and overall function assessed by a specialized gait laboratory.

Participants needed: 100
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: LifeBridge HealthUpdated: Jan 22, 2025Locations: 1
Eligibility criteria

Subject is male or non-pregnant female aged between 18 and 75 years of age. [+5]

Subject has a Body Mass Index (BMI) >40 [+4]

Status: Not yet recruiting

Comparison of Two Robotic-Assisted Total Knee Arthroplasty Systems

The goal of this prospective study is to compare two different knee replacement robots. This study will look at patient reported outcome measures and data collected during the operation. The main questions this study aims to answer include: * Will the patient reported outcomes differ between the two groups? * Will the intraoperative data differ between the two groups? Participants will undergo total knee replacement with one of the two robots, complete standardized surveys, and have x-rays taken.

Participants needed: 120
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Southeast Orthopedic SpecialistsUpdated: Apr 17, 2024
Eligibility criteria

Patient must be a candidate for primary TKA (either Stryker Triathlon with MAKO... [+4]

Patient has a Body Mass Index (BMI) > 40. [+12]