Knee Fracture

1

Review clinical trials related to Knee Fracture. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

pDIFFIR: Geriatric Periprosthetic DIstal Femur: FIxation Versus Replacement

Periprosthetic distal femur fractures are a significant source of morbidity and mortality for elderly patients. One treatment option involved a surgical fixation with plates or nails, screws and cables/wires along the side of your fractured bone. The second method consists in replacing your knee joint with an artificial knee prosthesis (artificial knee joint). The primary objective is to determine if acute distal femur replacement improves knee pain and functional outcomes compared to surgical fixation. Secondary outcomes are mortality, reoperation, complications, post-operative pain and quality of life. A health economic analysis will be conducted to assess the cost-effectiveness of both treatments. A total of 148 patients (74/group) will be enrolled in the study.

Participants needed: 148
Trial details
Age: 65+Biological sex: AllType: InterventionalSponsor: Unity Health TorontoUpdated: Dec 18, 2025Locations: 1
Eligibility criteria

• 65 years and older [+6]

• Active infection around the fracture (soft tissue or bone) [+11]