Knee Replacement

5

Review clinical trials related to Knee Replacement. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Optimizing a Remote-based Physical Activity Intervention for Adults With Total Knee Replacement

The purpose of this study is to identify which supplemental intervention components added to an online exercise program contribute to the greatest increases in physical activity (total MVPA and percent meeting guidelines \[≥150 min/week of MVPA\]) in adults with knee replacement at 6 and 12 months. Secondary outcomes will examine changes in pain and physical function.

Participants needed: 336
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of South CarolinaUpdated: May 5, 2026Locations: 1
Eligibility criteria

had a knee replacement (including primary, staged or independent bilateral, or r... [+5]

any contraindications to physical activity (e.g., chest pain) [+9]

Status: Recruiting

Investigating Patient Satisfaction With Smart Knee Implants

The main goal of this study is to see if there is a connection between the social and economic resources available in a patient's neighborhood (measured by the Area Deprivation Index, ADI) and their recovery after knee replacement surgery, as tracked through remote monitoring. A secondary goal is to find out if patients' self-reported pain and function score are linked to their actual physical improvement after surgery as measured by a remote therapeutic monitoring (RTM) device. Additionally, this study examines whether RTM can reduce the number of postoperative clinic visits within the first 90 days after surgery while maintaining patient satisfaction and patient-reported outcome measures (PROMs).

Participants needed: 150
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of ChicagoUpdated: Dec 17, 2025Locations: 1
Eligibility criteria

Patients over 18 years of age [+1]

Patients who receive contralateral knee replacement or contralateral or unilater... [+1]

Status: Not yet recruiting

Effect of Virtual Reality on Patient Outcomes and Satisfaction in Total Knee Replacement

This study aims to evaluate the effectiveness of virtual reality (VR) in managing preoperative anxiety and postoperative pain in patients undergoing total knee replacement. Investigators will assess the impact of preoperative VR training on anxiety levels, explore the effectiveness of relaxing and distracting VR videos for pain management after surgery, and determine the optimal timing for VR application by comparing different VR intervention times. Our goal is to identify how VR can improve both the emotional and physical recovery process for patients undergoing knee replacement surgery.

Participants needed: 64
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Aykut TurgutUpdated: Sep 26, 2025Locations: 1
Eligibility criteria

Patients with an ASA score of 1, 2, or 3 [+2]

Using >30 mg of oral oxycodone or equivalent daily [+10]

Status: Recruiting

The Medacta GMK SpheriKA Post-Marketing Surveillance Study

This is a Post-Marketing Surveillance of GMK SpheriKA knee stem prosthesis.

Participants needed: 281
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Medacta International SAUpdated: Sep 29, 2025Locations: 4
Eligibility criteria

Patients willing to sign the informed consent. [+4]

Patients with inflammatory arthritis. [+9]

Status: Recruiting

The Effect of Baduanjin on Patients Undergoing Knee Replacement Surgery

This randomized controlled trial aims to evaluate the effects of Baduanjin, a traditional Chinese mind-body exercise, on pain, comfort, and quality of recovery in patients undergoing total knee arthroplasty (TKA). The study will be conducted between July 2025 and July 2026 at Yalova Training and Research Hospital's Orthopedics Clinic. Sixty patients will be randomly assigned into two groups: an intervention group practicing Baduanjin and a control group receiving standard postoperative care. The intervention will begin on the first postoperative day and continue for three weeks. Outcome measures include the Visual Analog Scale (VAS) for pain, the General Comfort Questionnaire, and the Quality of Recovery-40 (QoR-40) questionnaire. These assessments will be conducted weekly for three weeks. The control group will follow routine postoperative care without Baduanjin. The primary objective is to determine whether Baduanjin can improve postoperative outcomes in terms of pain reduction, increased comfort, and better recovery quality.

Participants needed: 60
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Niran ÇobanUpdated: Aug 12, 2025Locations: 1
Eligibility criteria

Having undergone Knee Replacement Surgery under general anesthesia [+3]

Patients with contraindications to Baduanjin exercises, [+1]