Knee Surgery

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Review clinical trials related to Knee Surgery. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Comparison of Analgesic Efficacy and Impact on Motor Function in Knee Replacement Surgery: 0.1% Naropeine Tri-block Versus 0.5% Naropeine iPACK Saphenous Block - A Prospective Randomised Trial

Over the last two decades, perioperative analgesia has evolved. Spinal and epidural anaesthesia, once common, have been gradually phased out due to their side effects. The femoral block combined with the sciatic block, possibly with a perineural catheter, is now the gold standard for ensuring prolonged, high-quality analgesia. However, these blocks can cause muscle weakness in the quadriceps, limiting patients' functional recovery. To optimise functional rehabilitation, recent techniques favour more distal and selective blocks, such as the adductor canal (saphenous) block and the iPACK, which allow effective anaesthesia to be maintained whilst preserving motor function. However, these blocks do not always guarantee complete analgesia and may require additional blocks. The hypothesis of the current study is based on the idea that a proximal block targeting the femoral, obturator and sciatic nerves, administered with a low concentration of naropeine (0.1%), could provide more effective analgesia than a 0.5% saphenous iPACK block, whilst preserving motor function The originality of our approach in the current study lies in the use of dissociative proximal blocks performed with low concentrations of local anaesthetics, aimed at effectively covering the innervation of the knee whilst preserving motor function. The expected outcomes of this research are to optimise analgesic management for patients undergoing functional orthopaedic knee surgery, to promote early postoperative walking rehabilitation, to reduce the risk of chronic pain following knee arthroplasty, and to provide evidence to guide anaesthetic and post-surgical rehabilitation practices

Participants needed: 120
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: GCS Ramsay Santé pour l'Enseignement et la RechercheUpdated: May 11, 2026Locations: 1
Eligibility criteria

Age > 18 years; [+4]

Patients with an ASA score > 3; [+7]

Status: Not yet recruiting

Effects of Music Listening and Relaxation Interventions on Postoperative Recovery After Knee Surgery

This study aims to evaluate whether listening to music and using Emotional Freedom Techniques (EFT) can help patients recover better after knee arthroscopy. After this type of surgery, many patients experience pain, fear of movement (kinesiophobia), balance problems, and an increased risk of falling. In this study, patients will receive music listening and EFT as supportive, non-drug interventions during the postoperative period. The goal is to determine whether these simple and safe methods can reduce pain, decrease fear of movement, and lower fall risk, ultimately improving recovery. The findings of this study may help healthcare professionals, especially nurses, provide more holistic and patient-centered care after knee surgery.

Participants needed: 85
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Arzum ÇELİK BEKLEVİÇUpdated: Apr 15, 2026Locations: 1
Eligibility criteria

Aged between 18 and 65 years [+9]

Currently using psychiatric medications [+4]

Status: Not yet recruiting

Comparison of ACB With ACB and BiFeS Combination in Knee Arthroplasty Surgeries

The aim is to compare the postoperative analgesic effects of Adductor Canal and Biceps Femoris Short Head Blocks with Adductor Canal Block in patients undergoing Knee Arthroplasty surgery

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Cumhuriyet UniversityUpdated: Nov 25, 2025Locations: 1
Eligibility criteria

Adult patients over 18 years of age who underwent percutaneous nephrolithotomy u...

patients who did not give consent, [+9]

Status: Not yet recruiting

FH ORTHO SAS Knee Observatory

The objective of this observatory is to generate additional real life clinical data in accordance with local regulation (i.e. Post-Market Clinical Follow-up (PMCF) study, a study carried out following the European Conformity (CE) marking of a device and intended to answer specific questions relating to clinical safety or performance (i.e. residual risks) of a device when used in accordance with its approved instructions for use (IFU). The difficulty of such an observatory is to be able to collect data on the different versions of the devices, on the different possible combinations of implants of an knee arthroplasty. The observatory must also be able to cover devices used in ligament reconstruction surgery. The observatory will be based on the principle of a "dynamic" cohort during the inclusion period, i.e. with possible inclusions to replace the premature exits. Technical solutions will be implemented to facilitate data collection from surgeons (electronic Case Report Form (eCRF) and from patients (Electronic Patient Reported Outcome (ePRO) on smartphone/tablet/computer) when feasible. The data to be collected and the different follow-up times are based on our state-of-the-art, clinical evaluation plans and clinical evaluation reports.

Participants needed: 487
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: FH ORTHOUpdated: Feb 22, 2024Locations: 10
Eligibility criteria

Any patient undergoing or having undergone implantation of medical devices distr... [+3]

Infection, or latent infection [+12]